Results 251 to 260 of about 939,947 (330)

P-392. Use of Oral Tobramycin to Prevent Surgical Site Infections in the Setting of an Oral Neomycin Shortage for Patients Undergoing Colorectal Procedures: A Retrospective Chart Review

Skyler Radziszewski, Melanie Altar, Nicole M Ondrush, Gopi Patel, Victoria Adams-Sommer, Eleanor D Sadler, Andrew D. Santeusanio, Emily Walits, Polina Lerner   +8 more
openalex   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang, Haoyun Li, Hongfei Wang, Liangyu Shi, Ying Shing Chan, Yu Wang, Graham Ka Hon Shea   +6 more
wiley   +1 more source

Robot-assisted extraction of impacted mandibular tooth: a clinical report. [PDF]

BMC Oral Health
Miadili M, Zhang W, Zhang Y, Gao Y, Mutalifu H, Li X, Zhang J.   +6 more
europepmc   +1 more source

To evaluate the Anesthetic efficacy of 0.75%, 0.50% and 0.20% ropivacaine without vasoconstrictor in the minor and major Oral and Maxillofacial Surgical procedures [PDF]

Jagriti Lahiri, Dev Garg, Arun Rai
openalex   +1 more source

Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8‐AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen, Ji‐Jun Shan, Mo Chen, Zong Wu, Yi‐Ming Zhao, Hong‐Xu Zhu, Xin Jin, Yi‐Xiu Wang, Yi‐Bin Wu, Zhen Xiang, Zhi‐Wen Ding, Zhen‐Hai Lin, Long‐Rong Wang, Lu Wang   +13 more
wiley   +1 more source

Secondary Electron Hyperspectral Imaging of Carbons: New Insights and Good Practice Guide

Advanced Science, EarlyView.
Secondary hyperspectral imaging of carbon surfaces is assessed with reference materials and in comparison to standard spectroscopies. Characterization of functional carbon materials from battery research reveals otherwise inaccessible information about the distribution of sp2 and amorphous carbon, as shown in graphite anode and carbon coated lithium ...
James F. Nohl, Nicholas T.H. Farr, Maria Rosaria Acocella, Alexander J. Knight, Gareth M. Hughes, Jingqiong Zhang, Stuart Robertson, Stuart Micklethwaite, Sean Murphy, Tereza Motlová, Christopher Walker, Alexander I. Tartakovskii, Filip Mika, Zuzana Pokorná, Steve Tear, Andrew Pratt, Nancy L. Ford, Nicole Hondow, Mark A. E. Jepson, Lyudmila S. Mihaylova, Nik Reeves‐McLaren, Serena A. Cussen, Cornelia Rodenburg   +22 more
wiley   +1 more source

Novel ATR/PARP1 Dual Inhibitors Demonstrate Synergistic Antitumor Efficacy in Triple‐Negative Breast Cancer Models

Advanced Science, EarlyView.
Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao, Jiawei Zhou, Chen‐Chen Wang, Zong‐Hao Wang, Nian‐Dong Mao, Meng‐Lan He, Peng‐Peng Zhang, Ping Huang, Guo‐Wei Ye, Yu‐Qing Zhang, Feng‐Hui Tang, Hang Zhang, Tian Xie, Xiang‐Yang Ye   +13 more
wiley   +1 more source

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

Advanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen, Lingyun Yue, Yanna Pan, Bingying Jiang, Junfeng Wan, Haixia Lin, Fujiang Guo, Huiyu Li, Yajuan Li, Qingjie Zhao   +9 more
wiley   +1 more source

Paravertebral blocks and enhanced recovery after surgery protocols in breast reconstructive surgery: Patient selection and perspectives [PDF]

, 2018
Myckatyn, Terence M, Parikh, Rajiv P
core   +1 more source

Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis

Advanced Science, EarlyView.
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo, Yan Wang, Qiudi Liu, Zhaoyang Luo, Xiaomu Tian, Yuquan Wang, Yang Liu, Zhiwei Ning, Yingying Guo, Huiying Gao, Xinyue Wang, Jinglong Feng, Mengmeng Liu, Dina Saifullina, Yixin Zhang, Tengfei Pan, Yu Bian, Tao Ban, Tianyu Li, Yunyan Gu, Haihai Liang   +20 more
wiley   +1 more source