Results 51 to 60 of about 203,188 (294)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Moderate sedation for complex oral surgical procedures in the dental clinic

open access: yesIbom Medical Journal, 2021
Context: Intravenous sedation has become vastly employed in dental offices to manage anxiety and pain during surgical procedures. Several guidelines have focused on patient evaluation, safety of agents used, credentialling of operators, acquisition of ...
Osaguona AO, Osaiyuwu O
doaj   +1 more source

Acetylsalicylic Acid and Oral Surgical Procedure

open access: yesInternational journal of Emerging Trends in Science and Technology, 2016
1 Prinicipal Investigator, Department of Oral and Maxillofacial Surgery, Kist Medical College and Teaching Hospital, Lalitpur, Nepal 2 Associate Professor, Dept of Oral and Maxillofacial Surgery, Kist Medical College and Teaching Hospital, Lalitpur, Nepal Abstract Introduction: Acetylsalicylic acid (ASA) therapy, an antithrombotic agents used in ...
openaire   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

An adenomatoid odontogenic tumor in the mandibular region

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
The adenomatoid odontogenic tumor is a rare, non-aggressive, slow-growing and painless lesion that arises from the odontogenic epithelium. The maxillary region is the most affected one, predominating in the upper canine area. This study presents the case
David Pablo Guillén-Pérez   +2 more
doaj  

Management of biologics in oral surgery

open access: yesJournal of Oral Medicine and Oral Surgery, 2023
Biologics have revolutionised the management of immune-mediated inflammatory disorders, and their growing use has resulted in increasing numbers of these patients presenting in oral surgery settings.
Mills Sophie, Ryan Patrick, Gaffney Karl
doaj   +1 more source

Glove perforation during oral surgical procedures.

open access: yesMedicina oral, patologia oral y cirugia bucal, 2006
The aim of this study was to determine the incidence of glove perforation among undergraduates and residents performing maxillofacial surgery and identify procedures associated with the perforations.For this purpose, 200 pairs of surgical gloves were used.
Lopes de Freitas Xavier, Ruth   +3 more
openaire   +4 more sources

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