We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Acetylsalicylic Acid and Oral Surgical Procedure
1 Prinicipal Investigator, Department of Oral and Maxillofacial Surgery, Kist Medical College and Teaching Hospital, Lalitpur, Nepal 2 Associate Professor, Dept of Oral and Maxillofacial Surgery, Kist Medical College and Teaching Hospital, Lalitpur, Nepal Abstract Introduction: Acetylsalicylic acid (ASA) therapy, an antithrombotic agents used in ...
openaire +1 more source
Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan +12 more
wiley +1 more source
Moderate sedation for complex oral surgical procedures in the dental clinic
Context: Intravenous sedation has become vastly employed in dental offices to manage anxiety and pain during surgical procedures. Several guidelines have focused on patient evaluation, safety of agents used, credentialling of operators, acquisition of ...
Osaguona AO, Osaiyuwu O
doaj +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
Spectrum of oral and maxillofacial surgical procedures in Kano, Nigeria
The goal of the maxillofacial surgeon is to correct facial deformity while eradicating surgical diseases, prevent recurrence or complication and restore function. The aim of this paper is to review the surgical procedures carried out in a new tertiary teaching hospital.
S O, Ajike +4 more
openaire +2 more sources
The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma +5 more
wiley +1 more source
Perioperative Oral Nutritional Support For Patients Diagnosed With Primary Colon Adenocarcinoma Undergoing Radical Surgical Procedures -Peri-Nutri Trial: Study Protocol For A Randomized Controlled Trial. [PDF]
Raila Aro +9 more
openalex +3 more sources
An adenomatoid odontogenic tumor in the mandibular region
The adenomatoid odontogenic tumor is a rare, non-aggressive, slow-growing and painless lesion that arises from the odontogenic epithelium. The maxillary region is the most affected one, predominating in the upper canine area. This study presents the case
David Pablo Guillén-Pérez +2 more
doaj

