Results 171 to 180 of about 2,052,976 (276)
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
Clinical myths in dental bleaching: an evidence-based structured narrative review. [PDF]
Reis A +6 more
europepmc +1 more source
Heroic Register, Oral Tradition, and the Alliterative Morte Arthure [PDF]
Rebecca Richardson Mouser
doaj
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong +9 more
wiley +1 more source
The Metonym: Rhetoric and Oral Tradition at the Crossroads [PDF]
Catherine Quick
doaj
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin +23 more
wiley +1 more source
On the transmission of texts: Written cultures as complex systems. [PDF]
Camps JB, Randon-Furling J, Godreau U.
europepmc +1 more source
Hear the Tale of the Famine Year”: Famine Policy, Oral Traditions, and the Recalcitrant Voice of the Colonized in Nineteenth-Century India [PDF]
Gloria Goodwin Raheja
doaj
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma +12 more
wiley +1 more source

