Results 131 to 140 of about 1,050,854 (350)

The Fate of RPE Cells Following hESC-RPE Patch Transplantation in Haemorrhagic Wet AMD: Pigmentation, Extension of Pigmentation, Thickness of Transplant, Assessment for Proliferation and Visual Function—A 5 Year-Follow Up

Diagnostics
(1) Background: We reviewed a stem cell-derived therapeutic strategy for advanced neovascular age-related macular degeneration (nAMD) using a human embryonic stem cell-derived retinal pigment epithelium (hESC-RPE) monolayer delivered on a coated ...
Lyndon da Cruz, Taha Soomro, Odysseas Georgiadis, Britta Nommiste, Mandeep S. Sagoo, Peter Coffey   +5 more
doaj   +1 more source

Calculating the transport properties of magnetic materials from first principles including thermal and alloy disorder, noncollinearity, and spin-orbit coupling [PDF]

, 2018
A.A. Starikov, Yi Liu, Zhe Yuan, Paul J. Kelly   +3 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Orbital-selective Mott phase in multiorbital models for iron pnictides and chalcogenides [PDF]

, 2017
Rong Yu, Qimiao Si
openalex   +1 more source

Robust Modeling of GNSS Orbit and Clock Error Dynamics [PDF]

, 2022
Elisa Gallon, Mathieu Joerger, Boris Pervan   +2 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Spin-0 Mott insulator to metal to spin-1 Mott insulator transition in the single-orbital Hubbard model on the decorated honeycomb lattice [PDF]

, 2021
H. L. Nourse, Ross H. McKenzie, B. J. Powell   +2 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Ice Giant Systems: The scientific potential of orbital missions to Uranus and Neptune

, 2020
Leigh N. Fletcher, Ravit Helled, E. Roussos, G. H. Jones, S. Charnoz, Nicolás André, D. J. Andrews, Michele T. Bannister, E. J. Bunce, T. Cavalié, F. Ferri, Jonathan J. Fortney, D. Grassi, Léa Griton, P. Hartogh, R. Hueso, Yohai Kaspi, Laurent Lamy, A. Masters, Henrik Melin, Julianne I. Moses, O. Mousis, Nadine Nettleman, Christina Plainaki, Jürgen Schmidt, Amy Simon, G. Tobie, Paolo Tortora, F. Tosi, D. Turrini   +29 more
openalex   +2 more sources

Machine learning detection of dust impact signals observed by the Solar Orbiter [PDF]

, 2023
Andreas Kvammen, Kristoffer Wickstrøm, Samuel Kočiščák, Jakub Vaverka, Libor Nouzák, Arnaud Zaslavsky, Kristina Racković Babić, Amalie Gjelsvik, David Píša, J. Souček, Ingrid Mann   +10 more
openalex   +1 more source