Results 161 to 170 of about 1,149,056 (292)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

MEMANFAATKAN ORBIT SATELIT YANG SALING BERSILANGAN UNTUK. MENENTUKAN KETINGGIAN PERMUKAAN TANAH DARI PUSAT BUMI

, 1994
Ringkasan Bertolak dari keadaan orbit-orbit satelit yang saling silang menyilang jauh diatas permukaan bumi sangat banyak, dapat dinianfaatkan untuk menghitung ketinggian permukaan tanah pada titik tepat di bawah orbit-orbit satelit yang saling ...
Dede Rachmat
core  

Assisted Snapshot GNSS Position, Navigation, and Timing for LEO Satellites. [PDF]

Sensors (Basel)
Kim S, Holmes T, Schmitz T, Wardall G, Akos D.   +4 more
europepmc   +1 more source

Spin currents and spin–orbit torques in ferromagnetic trilayers

Nature Materials, 2018
S. Baek, V. Amin, Young-Wan Oh, Gyungchoon Go, Seung-Jae Lee, Geun-Hee Lee, Kab-Jin Kim, M. Stiles, Byong-Guk Park, Kyung-Jin Lee   +9 more
semanticscholar   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The orbital dynamics of the LMC and SMC about the Milky Way. [PDF]

Astron Astrophys Rev
Besla G, Kallivayalil N.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Adaptive Weighting-Based Multi-Station Doppler Orbit Determination for Noncooperative LEO Satellites. [PDF]

Sensors (Basel)
Lei M, Liu Y, Yang Z, Li H, Fang Z.
europepmc   +1 more source

Field-free switching of a perpendicular magnetic tunnel junction through the interplay of spin–orbit and spin-transfer torques

Nature Electronics, 2018
Mengxing Wang, Wen-Long Cai, Dao-Qian Zhu, Zhao-Hao Wang, Jimmy J. Kan, Zhengyang Zhao, K. Cao, Zi-Lu Wang, You-Guang Zhang, Tianrui Zhang, Chando Park, Jian-Ping Wang, A. Fert, Wei-Sheng Zhao   +13 more
semanticscholar   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source