A Caseof Aneurism by Anastomosis in the Left Orbit, Cured by Tying the Common Trunk of the Left Carotid Artery [PDF]
William Dalrymple
openalex +1 more source
Discussion on Injuries and Inflammatory Diseases Affecting the Orbit and Accessory Sinuses [PDF]
E. D. D. Davis
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Effect of oral propranolol on periocular Capillary Hemangiomas of Infancy
Background: To assess the safety and efficacy of oral propranolol in the management of periocular Capillary Hemangiomas of Infancy (CHI). Methods: Medical records of 21 infants diagnosed with periocular capillary hemangioma during a period of 5 years ...
Kirthi Koka+2 more
doaj
CASE OF ERECTILE TUMOUR OF THE ORBIT, CURED BY INFILTRATION WITH THE SOLUTION OF THE LACTATE OF IRON AND PUNCTURE WITH HOT NEEDLES, AFTER THE LIGATURE OF THE CAROTID ARTERY HAD FAILED; [PDF]
Daniel Brainard
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Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik+4 more
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Design of Space Target Surveillance Constellation Based on Simulation Comparison Method. [PDF]
Hu Q, Liu D, Dong Z.
europepmc +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian+10 more
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Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source