Determination of the Orbital Moment and Crystal-Field Splitting in
, 2005 M. W. Haverkort +20 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Improving the GRACE Kinematic Precise Orbit Determination Through Modified Clock Estimating. [PDF]
Sensors (Basel), 2019 Zhou X, Jiang W, Chen H, Li Z, Liu X.
europepmc +1 more source
Determination of the force transmitted by an ion thruster plasma plume to an orbital object
, 2015 А.P. Alpatov +5 more
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Distributed Orbit Determination for Global Navigation Satellite System with Inter-Satellite Link. [PDF]
Sensors (Basel), 2019 Wen Y, Zhu J, Gong Y, Wang Q, He X.
europepmc +1 more source
Reduced-Dynamic Orbit Determination of Low-Orbit Satellites Taking into Account GNSS Attitude Errors [PDF]
L. Liu +3 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Determination of onboard coplanar orbital maneuvers with orbits determined using GPS
, 2014 In the present paper a study is made in order to find an algorithm that can calculate coplanar orbital maneuvers for an artificial satellite. The idea is to find a method that is fast enough to be combined with onboard orbit determination using GPS data collected from a receiver that is located in the satellite.
Chiaradia, Ana Paula Marins +2 more
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Towards an analytical theory of the third-body problem for highly elliptical orbits
, 2016 When dealing with satellites orbiting a central body on a highly elliptical orbit, it is necessary to consider the effect of gravitational perturbations due to external bodies. Indeed, these perturbations can become very important as soon as the altitude
Deleflie, Florent +2 more
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