Results 181 to 190 of about 3,161,815 (352)

Determination of the force transmitted by an ion thruster plasma plume to an orbital object

open access: bronze, 2015
А.P. Alpatov   +5 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Study of a homotopy continuation method for early orbit determination with the Tracking and Data Relay Satellite System (TDRSS) [PDF]

open access: yes
A recent mathematical technique for solving systems of equations is applied in a very general way to the orbit determination problem. The study of this technique, the homotopy continuation method, was motivated by the possible need to perform early orbit
Huang, C., Smith, R. L.
core   +1 more source

ORBIT DETERMINATION OF HILDA AND THULE ASTEROIDS [PDF]

open access: diamond, 2013
M. A. Sharaf   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Towards an analytical theory of the third-body problem for highly elliptical orbits

open access: yes, 2016
When dealing with satellites orbiting a central body on a highly elliptical orbit, it is necessary to consider the effect of gravitational perturbations due to external bodies. Indeed, these perturbations can become very important as soon as the altitude
Deleflie, Florent   +2 more
core  

Robust Onboard Orbit Determination Through Error Kalman Filtering [PDF]

open access: gold
Michele Ceresoli   +3 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Long and short arc altitude determination for GEOS-C [PDF]

open access: yes
The accuracy with which the GEOS-C altitude may be estimated over long (7 day) and short (40 minute) orbital arcs is investigated. Over the long are excellent agreement was attained between a simulation of the orbit determination process and a covariance
Argentiero, P., Kahn, W. D., Koch, D.
core   +1 more source

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