Results 171 to 180 of about 1,146,792 (246)

Sclerotherapy in Orbital Dermoid Cysts: A Promising Minimally Invasive Approach

Surgical excision has been the treatment of choice for orbital dermoid cysts but can be associated with complications and aesthetic concerns. We aim to study the efficacy and safety of sclerotherapy, a minimally invasive approach, in managing dermoid ...
Rachna Agarwal; Ankita Aishwarya
core  

Linkage Engineering Boosts Battery Performance of Two‐Electron Phenothiazine‐Based Polyamide Cathodes

Advanced Science, EarlyView.
Three phenothiazine‐based polyamides featuring gradually strengthened electron‐withdrawing linkers are developed as high‐voltage cathodes for lithium‐organic batteries. The linker motif serves not only as a structural bridge to suppress solubility, but also as a functional design element that governs optoelectronic properties and electron/ion transport
Shujuan Cao, Chunping Ren, Jing Qin, Xiujuan Wang, Xiaoming He   +4 more
wiley   +1 more source

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

A Multi‐Targeting Chimeric Antigen Receptor‐T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang, Yanlei Zhang, Shuixiu Peng, Chenchen Hou, Huaqi Guo, Tianyu Zhou, Alex H. Chang, Lifeng Yan, Weining Xiong   +8 more
wiley   +1 more source

Bilateral Orbital Cellulitis Causing Septic Pulmonary Embolism and Subsequent Bilateral Pneumothorax: A Rare Case Report

International Medical Case Reports Journal
Faisal Abdi Osoble Osman,1 Ibrahim Mohamed Hirsi,2 Shuayb Moallim Ali Jama,1 Abdirisak Abdikarin Ahmed,3 Abdisalam Abdullahi Yusuf,2 Mohamed Osman Dahir1 1Radiology Department, Mogadishu Somali Turkey, Recep Tayyip Erdogan Training and Research Hospital,
Osman FAO, Hirsi IM, Ali Jama SM, Ahmed AA, Yusuf AA, Dahir MO   +5 more
doaj  

Invasive Sinusitis Presenting with Orbital Complications in COVID Patients: Is Mucor the Only Cause? [PDF]

Indian J Otolaryngol Head Neck Surg
Mohammadi K, Mohiyuddin SMA, Prasad KC, Rajan A, Indu Varsha G, Natrajan A, Sakalecha AK, Jose DA.   +7 more
europepmc   +1 more source

Sonogenetic Control of Engineered Probiotics for the Treatment of MASH by Modulating the Gut‐Liver Axis

Advanced Science, EarlyView.
Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji, Yan Fang, Shen Zhang, Weichen Xu, Wenyun Guo, Jing Chen, Mingrui Zhu, Congjian Wen, Siming Chen, Yuli Zhu, Huixiong Xu, Haohao Yin   +11 more
wiley   +1 more source

Unraveling the Effects of Depolarization in Ultrathin Barium Titanate

Advanced Science, EarlyView.
This article employs synchrotron‐based spectroscopy, time‐resolved electrical measurements, and phase‐field simulations to establish reverse‐domain formation as the mechanism of polarization loss in ultrathin BaTiO3${\rm BaTiO}_3$ films as a critical obstacle to low‐voltage ferroelectric devices.
Thomas Lee, Prabhat Kumar, Christoph Klewe, Pravin Kavle, Padraic Shafer, Zhi (Jackie) Yao, Lane W. Martin   +6 more
wiley   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source