A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang +9 more
wiley +1 more source
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee +8 more
wiley +1 more source
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
A survey of public eye-care behavior and myopia education
PurposeTo investigate the prevalence of myopia, analyze public eye care behaviors, eye protective practices, and concerns regarding myopia among different age demographics.
Qianwen Liu +28 more
doaj +1 more source
Development of a species-specific coproantigen ELISA for human taenia solium taeniasis [PDF]
Taenia solium causes human neurocysticercosis and is endemic in underdeveloped countries where backyard pig keeping is common. Microscopic fecal diagnostic methods for human T.
Allan, JC +7 more
core
Spectrally Tunable 2D Material‐Based Infrared Photodetectors for Intelligent Optoelectronics
Intelligent optoelectronics through spectral engineering of 2D material‐based infrared photodetectors. Abstract The evolution of intelligent optoelectronic systems is driven by artificial intelligence (AI). However, their practical realization hinges on the ability to dynamically capture and process optical signals across a broad infrared (IR) spectrum.
Junheon Ha +18 more
wiley +1 more source
Expression of Tumor Assosiated and Epithelial-mesenchymal Transition Markers in 2d and 3d Cell Cultures of Mcf-7 [PDF]
The target effects on the expression of epithelial-mesenchymal transition regulation molecules are promising for cancer therapy, including breast cancer.
Herheliuk, T. (Tetiana) +4 more
core +2 more sources
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird +8 more
wiley +1 more source
Mechanistic study of targeting melanoma with STING pathway deficiencies via PIKfyve inhibitor
Objective·To explore the antitumor effects and potential mechanisms of combining phosphoinositide 3-kinase, FYVE-type zinc finger containing (PIKfyve) inhibitor YM201636 with the stimulator of interferon genes (STING) agonist diABZI in STING pathway ...
YANG Xiaoyu +5 more
doaj +1 more source
Variability in Nonvitamin K Oral Anticoagulant Dose Eligibility and Adjustment According to Renal Formulae and Clinical Outcomes in Patients With Atrial Fibrillation With and Without Chronic Kidney Disease: Insights From ORBIT‐AF II [PDF]
Ren Jie Robert Yao +5 more
openalex +1 more source

