Results 191 to 200 of about 102,497 (301)
Advanced Science, EarlyView.ABSTRACT Diabetic wounds are characterized by persistent inflammation and impaired immune resolution, yet the therapeutic translation of single‐cell atlases into rational immunomodulatory strategies remains limited. Here, integration of diabetic‐wound single‐cell transcriptomic datasets identifies a neutrophil subpopulation enriched in cluster of ...
Tairong Cui +12 more
wiley +1 more source
Time to rethink circadian rhythms beyond the transcriptome. [PDF]
J BiochemOtobe Y, Yoshitane H.
europepmc +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis (CRS) is frequently associated with polymicrobial biofilms involving Staphylococcus aureus and Pseudomonas aeruginosa. Interactions between these organisms are thought to influence disease severity, but the epithelial effects of exoproteins derived from patient‐matched cocultures remain poorly defined ...
Xiaohan Sun +6 more
wiley +1 more source
Functional Specialization of Respiratory and Olfactory Mucus Revealed by Proteomic Profiling
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Mucus overlies the nasal mucosa in the respiratory and olfactory regions, which perform distinct physiological functions. However, proteomic differences between respiratory mucosa (RM) and olfactory cleft (OC) mucus remain unclear.
Anna Kristina Hernandez +7 more
wiley +1 more source
Profiling and Identification of Novel Tiletamine Metabolites in Human Urine and Hair by Liquid Chromatography Coupled With Quadrupole-Orbitrap Mass Spectrometry. [PDF]
Rapid Commun Mass SpectromQin S +8 more
europepmc +1 more source
Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology
Annals of Neurology, EarlyView.Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby +6 more
wiley +1 more source
Implementation of Nonisobaric TMT Analogs for Accurate Precursor-Level Quantification by plexDIA. [PDF]
Rapid Commun Mass SpectromWei TY, Paulo JA.
europepmc +1 more source
Journal of the American Oil Chemists' Society, EarlyView.ABSTRACT Microalgal oil is a sustainable source of omega‐3 polyunsaturated fatty acids. However, it is very sensitive to lipid oxidation, especially in emulsions. While the presence of phospholipids and galactolipids in microalgal oil can influence its oxidation, their impact in oil‐in‐water emulsion is not yet fully understood. This study investigates
Weiwei Sun +2 more
wiley +1 more source
Exploratory Measurements of Singly Substituted and Clumped Isotopologues in Iodate Using Electrospray Ionization Mass Spectrometry. [PDF]
Rapid Commun Mass SpectromLucarelli J +6 more
europepmc +1 more source
Arthroscopy, EarlyView.Purpose To examine systemic exposure and elution characteristics of liquid vancomycin‐soaked anterior cruciate ligament (ACL) grafts in vivo by assessing serum vancomycin levels over 48 hours after ACL reconstruction and comparing the resulting concentrations with the toxic threshold of 15 to 20 μg/mL.
Swen Witteveen +8 more
wiley +1 more source