Results 121 to 130 of about 551,491 (329)

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Tumor of the Orbit, by Extension to Frontal and Temporal Regions, Treated by X-Rays [PDF]

, 1918
William M. Sweet
openalex   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Cylindrically and spherically constrained families of non-Keplerian orbits [PDF]

, 2013
This paper introduces new families of Sun-centered non-Keplerian orbits (NKOs) that are constrained to a three-dimensional surface such as a cylinder or sphere. As such, they are an extension to the well-known families of two dimensional NKOs.
Heiligers, Jeannette, McInnes, Colin
core  

LXI. The forms of planetary orbits on the theory of relativity [PDF]

, 1921
W.B. Morton
openalex   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

On the Action of a Subgroup of the Modular Group on Imaginary Quadratic Number Fields

Axioms
Consider the modular group PSL(2,Z)=⟨x,y|x2=y3=1⟩ generated by the transformations x:z↦−1/z and y:z↦(z−1)/z. Let H be the proper subgroup ⟨y,v|y3=v3=1⟩ of PSL(2,Z), where v=xyx.
Abdulaziz Deajim
doaj   +1 more source

Bifurcations of Orbit and Inclination Flips Heteroclinic Loop with Nonhyperbolic Equilibria

The Scientific World Journal, 2014
The bifurcations of heteroclinic loop with one nonhyperbolic equilibrium and one hyperbolic saddle are considered, where the nonhyperbolic equilibrium is supposed to undergo a transcritical bifurcation; moreover, the heteroclinic loop has an orbit flip ...
Fengjie Geng, Junfang Zhao
doaj   +1 more source

On the Orbit of Jupiter's Eighth Satellite.: (Plate 16.) [PDF]

, 1909
P. H. Cowell, A. C. D. Crommelin, Carl Davidson   +2 more
openalex   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source