Results 1 to 10 of about 34,549 (114)

Comparative Effectiveness of Cytisinicline and Varenicline for Smoking Cessation: A Matching-Adjusted Indirect Comparison (MAIC) [PDF]

open access: yesJournal of Health Economics and Outcomes Research
# Background Pharmacologic options for supporting smoking cessation remain limited. Cytisinicline is a plant-based alkaloid that selectively binds to α4β2 nicotinic acetylcholine receptors, reducing nicotine craving and withdrawal symptoms, and has ...
Mark Rubinstein   +3 more
doaj   +2 more sources

Evaluating different scoring algorithms to assess communication ability for individuals living with Angelman syndrome: the Observer-Reported Communication Ability (ORCA) measure [PDF]

open access: yesJournal of Patient-Reported Outcomes
Background Many neurodevelopmental disorders are associated with significantly impaired communication that impacts the individuals and their families’ daily activities.
Bryce B. Reeve   +7 more
doaj   +2 more sources

Novel evidence of interaction between killer whales (Orcinus orca) and juvenile white sharks (Carcharodon carcharias) in the Gulf of California, Mexico

open access: yesFrontiers in Marine Science
White sharks (Carcharodon carcharias), have only one known natural predator in the ocean, the orca or killer whale (Orcinus orca). While interactions between these coexisting apex predators are known to occur, killer whales are adept at subduing adult ...
Salvador J Jorgensen   +1 more
exaly   +3 more sources

Killer whales (Orcinus orca) hunt, kill and consume the largest fish on Earth, the whale shark (Rhincodon typus)

open access: yesFrontiers in Marine Science
Killer whales (Orcinus orca) are the apex predator in global oceans, and as such they are afforded access to prey species at all trophic levels and sizes.
Francesca Pancaldi   +6 more
exaly   +3 more sources

Comprehensive mapping of RNA modification dynamics and crosstalk via deep learning and nanopore direct RNA-sequencing [PDF]

open access: yesNature Communications
Despite the extensive studies of individual RNA modifications, the lack of methods to detect multiple modification types simultaneously has left the global epitranscriptomic landscape and its underlying crosstalk largely unexplored. Here, we present ORCA
Han Dong   +6 more
doaj   +2 more sources

Stereotyped whistles in southern resident killer whales [PDF]

open access: yesPeerJ, 2021
The endangered Southern Resident killer whales (Orcinus orca) of the northeast Pacific region use two main types of vocal signals to communicate: discrete calls and whistles.
Marie Souhaut, Monika W. Shields
doaj   +2 more sources

STUDY OF THE STABILITY OF THE SUBSTANCE 3-[2-(4-PHENYL-1-PIPERAZINO)-2-OXOETHYL]QUINAZOLINE-4(3Н)-ONE UNDER STRESSFUL CONDITIONS

open access: yesФармация и фармакология (Пятигорск), 2021
The aim of the research was to study the stability of a new pharmaceutical substance 3-[2-(4-phenyl-1-piperazino)-2-oxoethyl]quinazoline-4(3Н)-one under stress conditions.Materials and methods.
T. A. Gendugov   +3 more
doaj   +1 more source

Citizen science in the marine environment: estimating common dolphin densities in the north-east Atlantic [PDF]

open access: yesPeerJ, 2020
Background Citizen science is increasingly popular and has the potential to collect extensive datasets at lower costs than traditional surveys conducted by professional scientists.
James R. Robbins   +2 more
doaj   +2 more sources

Open tibial shaft fractures: treatment patterns in sub-Saharan Africa

open access: yesOTA International, 2023
. Objective:. Open tibial shaft fractures are a leading cause of disability worldwide, particularly in low and middle-income countries (LMICs). Guidelines for these injuries have been developed in many high-income countries, but treatment patterns across
ORCA Study Group
doaj   +1 more source

Bias and Misrepresentation of Science Undermines Productive Discourse on Animal Welfare Policy: A Case Study

open access: yesAnimals, 2020
Reliable scientific knowledge is crucial for informing legislative, regulatory, and policy decisions in a variety of areas. To that end, scientific reviews of topical issues can be invaluable tools for informing productive discourse and decision-making ...
Kelly Jaakkola   +4 more
doaj   +1 more source

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