Results 61 to 70 of about 42,436 (244)

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

Perspective: The Future of the Southern Resident Killer Whales Depends on Interactions With Other Killer Whale Populations

Ecology and Evolution
Ecological and genetic interactions among conspecific populations play an important role in population viability, but these interactions are not always fully considered in strategies to recover endangered taxa.
Michael J. Ford, Eric J. Ward, Marty Kardos, Kim M. Parsons, Candice Emmons, M. Bradley Hanson   +5 more
doaj   +1 more source

Orca (Orcinus orca) observations in the Arabian (Persian) Gulf

, 2022
Orca (Orcinus orca) observations in the Arabian (Persian ...
Salah Jazzaf (14103527), Talal Dashti (14103524), James M. Bishop (3331224)   +2 more
core   +1 more source

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Advanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

Woodward Canyon Japanese Market Wine Fact Sheet [PDF]

, 2015
Japanese-language wine fact sheets created by Orca International advertise wines from Woodward Canyon Winery in Walla Walla, Washington. Featured wines are Chardonnay, Estate Chardonnay Walla Walla Valley, Barbera, Merlot, Cabernet Sauvignon Artist ...
ORCA International
core   +1 more source

Operando Visualization of Cathode Water Management in Proton Exchange Membrane Water Electrolyzers Using Synchrotron X‐Ray Radiography

Advanced Science, EarlyView.
The cathode of proton exchange membrane water electrolyzers remains a poorly understood region despite its importance for hydrogen purity and operational safety. Operando synchrotron X‐ray radiography directly visualizes liquid water behavior and uncovers a transition from continuous to pulsating transport, providing new insight into multiphase ...
Wataru Yoshimune, Tetsuichiro Hayakawa, Yuta Miyase   +2 more
wiley   +1 more source

Orca – Orcinus orca (Linnaeus, 1758) [PDF]

, 2017
Mamíferos - Orden Cetacea - Familia Delphinidae en la Enciclopedia Virtual de Vertebrados Españoles, http://www.vertebradosibericos.org/. Versiones anteriores: 20-06-2011A comprehensive review of the natural history of the Killer Whale Orcinus orca in ...
Miján, Ismael, Suárez-Esteban, Alberto, Salvador Milla, Alfredo   +2 more
core   +1 more source

Flame Suppression in Lithium‐Ion Batteries During Thermal Runaway Through Solvent Design Considering the Volatility–Flammability Relationship

Advanced Science, EarlyView.
An asymmetric sulfonate solvent forms thermally stable interphases and demonstrates non‐flammability, suppressing heat accumulation for safer, high‐performance lithium‐ion batteries. ABSTRACT An asymmetric sulfonate‐based linear solvent, 2,2,2‐trifluoromethyl mesylate (FMS), is designed and used as the primary solvent in liquid electrolytes to enhance ...
Chi‐Yeong Hong, Joon Ha Chang, Ho Yeon Jang, Jooeun Byun, Chae Rim Lee, Jeongmin Kim, Oh B. Chae, Youngjin Kim, Jun Ho Song, Chihyun Hwang, Seoin Back, Ki Jae Kim, Hyun‐seung Kim   +12 more
wiley   +1 more source

Organizational Readiness for Change Depends on Facility Complexity When Developing a National Stewardship Intervention

Antimicrobial Stewardship & Healthcare Epidemiology
Introduction: The organizational readiness for change assessment survey (ORCA) is a tool to assess a site’s readiness for implementation and identify barriers to change.
Eva Amenta, Larissa Grigoryan, Sophia Braund, David Ramsey, John Donnelly, Rogelio Hernandez, Aanand Naik, Barbara Trautner   +7 more
doaj   +1 more source