Results 1 to 10 of about 317,067 (243)

A systematic review of clinical effectiveness and safety for historical and current treatment options for metachromatic leukodystrophy in children, including atidarsagene autotemcel

open access: yesOrphanet Journal of Rare Diseases, 2023
Objective To understand the benefit-risk profile for historical and current treatments for MLD. Methods A systematic review was conducted on the effectiveness, safety, and costs of MLD treatments: allogeneic haematopoietic stem cell transplantation (HSCT)
Nigel Armstrong   +3 more
doaj   +1 more source

Assessment of vaccination service delivery and quality: a cross-sectional survey of over 1300 health facilities from 29 districts in Sindh, Pakistan conducted between 2017–18

open access: yesBMC Health Services Research, 2022
Background Routine childhood immunization coverage in Pakistan remains sub-par, in part, due to suboptimal utilization of existing vaccination services.
Danya Arif Siddiqi   +7 more
doaj   +1 more source

A proof-of-concept analysis of carbohydrate-deficient transferrin by imaged capillary isoelectric focusing and in-capillary immunodetection

open access: yesBioTechniques, 2020
Carbohydrate-deficient transferrin (CDT) is a reliable biomarker for chronic alcohol abuse. We developed a method for CDT analysis by capillary isoelectric focusing, followed by immunodetection directly in the capillary, in an automated fashion and on a ...
Jiaqi Wu   +3 more
doaj   +1 more source

Potential Markers for Selecting Self-Eliminating Apple Genotypes

open access: yesPlants, 2021
The heavy blooming of apple trees results in the inefficient usage of energy and nutritional material, and additional expenditure on fruitlet thinning is required to maintain fruit quality.
Aurelijus Starkus   +6 more
doaj   +1 more source

A mobile swabbing booth to address Singapore GPs’ concerns about swabber protection: human-centred design during the COVID-19 pandemic

open access: yesBMC Family Practice, 2021
Background During the COVID-19 pandemic, the Ministry of Health asked Singapore’s private general practitioners (GPs) to perform swab testing in their clinics, but some GPs had concerns about swabber protection. Our aim was to develop a swabbing booth to
Boon See Teo   +5 more
doaj   +1 more source

Grassy-floral soil covering as a tool for increasing herbaceous diversity in agroforestry [PDF]

open access: yesJournal of Central European Agriculture, 2022
Intensive agricultural technologies lead to a simplification of landscape and a decrease in biodiversity. Besides economic benefits, alley cropping might increase species richness, improving pollination in agriculture.
Nóra Szigeti   +3 more
doaj   +1 more source

Understanding caregiver descriptions of initial signs and symptoms to improve diagnosis of metachromatic leukodystrophy

open access: yesOrphanet Journal of Rare Diseases, 2022
Background Metachromatic leukodystrophy (MLD), a relentlessly progressive and ultimately fatal condition, is a rare autosomal recessive lysosomal storage disorder caused by a deficiency of the enzyme arylsulfatase A (ARSA).
F. Eichler   +9 more
doaj   +1 more source

Behavioral recommendation engine driven by only non-identifiable user data

open access: yesMachine Learning with Applications, 2023
Most recommendation systems utilize personal data to device personalized recommendations for users. Even though it seems favorable, security risks like data breaches are inevitable.
Kishor Datta Gupta   +4 more
doaj   +1 more source

The effect of osmotic stress, lighting spectrum and temperature on growth and gene expression related to anthocyanin biosynthetic pathway in wild strawberry (Fragaria vesca L.) in vitro

open access: yesFolia Horticulturae, 2023
The goal of this research was to evaluate the effect of light, temperature, sucrose and PEG on the growth of Fragaria vesca in vitro and the expression of regulatory Myb10, WD40 and enzyme-coding genes CHI, CHS, DFR, EGL, F3H and UFGT, which are ...
Vinskienė Jurgita   +4 more
doaj   +1 more source

Multilocus sequence typing (MLST) methods for the emerging Campylobacter species C. hyointestinalis, C. lanienae, C. sputorum, C. concisus and C. curvus

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Multilocus sequence typing (MLST) systems have been reported previously for multiple food- and food animal-associated Campylobacter species (e.g. C. jejuni, C. coli, C. lari and C. fetus) to both differentiate strains and identify clonal lineages. These
William G Miller   +9 more
doaj   +1 more source

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