Results 1 to 10 of about 32,606 (253)

A systematic review of clinical effectiveness and safety for historical and current treatment options for metachromatic leukodystrophy in children, including atidarsagene autotemcel

Orphanet Journal of Rare Diseases, 2023
Objective To understand the benefit-risk profile for historical and current treatments for MLD. Methods A systematic review was conducted on the effectiveness, safety, and costs of MLD treatments: allogeneic haematopoietic stem cell transplantation (HSCT)
Nigel Armstrong, Andrew Olaye, Caro Noake, Francis Pang   +3 more
doaj   +1 more source

Assessment of vaccination service delivery and quality: a cross-sectional survey of over 1300 health facilities from 29 districts in Sindh, Pakistan conducted between 2017–18

BMC Health Services Research, 2022
Background Routine childhood immunization coverage in Pakistan remains sub-par, in part, due to suboptimal utilization of existing vaccination services.
Danya Arif Siddiqi, Sara Abdullah, Vijay Kumar Dharma, Tasleem Khamisani, Mubarak Taighoon Shah, Hamidreza Setayesh, Aamir Javed Khan, Subhash Chandir   +7 more
doaj   +1 more source

A proof-of-concept analysis of carbohydrate-deficient transferrin by imaged capillary isoelectric focusing and in-capillary immunodetection

BioTechniques, 2020
Carbohydrate-deficient transferrin (CDT) is a reliable biomarker for chronic alcohol abuse. We developed a method for CDT analysis by capillary isoelectric focusing, followed by immunodetection directly in the capillary, in an automated fashion and on a ...
Jiaqi Wu, Charles H Haitjema, Christopher D Heger, Annegret Boge   +3 more
doaj   +1 more source

Behavioral recommendation engine driven by only non-identifiable user data

Machine Learning with Applications, 2023
Most recommendation systems utilize personal data to device personalized recommendations for users. Even though it seems favorable, security risks like data breaches are inevitable.
Kishor Datta Gupta, Nafiz Sadman, Akib Sadmanee, Md. Kamruzzaman Sarker, Roy George   +4 more
doaj   +1 more source

A mobile swabbing booth to address Singapore GPs’ concerns about swabber protection: human-centred design during the COVID-19 pandemic

BMC Family Practice, 2021
Background During the COVID-19 pandemic, the Ministry of Health asked Singapore’s private general practitioners (GPs) to perform swab testing in their clinics, but some GPs had concerns about swabber protection. Our aim was to develop a swabbing booth to
Boon See Teo, Esther Li, Yi-Lin Khoo, Michelle Evaristo, Yang Fang, Helen E. Smith   +5 more
doaj   +1 more source

Understanding caregiver descriptions of initial signs and symptoms to improve diagnosis of metachromatic leukodystrophy

Orphanet Journal of Rare Diseases, 2022
Background Metachromatic leukodystrophy (MLD), a relentlessly progressive and ultimately fatal condition, is a rare autosomal recessive lysosomal storage disorder caused by a deficiency of the enzyme arylsulfatase A (ARSA).
F. Eichler, Caroline Sevin, M. Barth, F. Pang, K. Howie, M. Walz, A. Wilds, C. Calcagni, C. Chanson, L. Campbell   +9 more
doaj   +1 more source

Methods for quantifying rain-splash dispersal of Neonectria ditissima conidia in apple canopies

Frontiers in Horticulture, 2023
Many microorganisms can be dispersed by rain-splash, whereby spores become suspended in water and are spread via droplets. The resulting dispersal gradient is dependent on several factors including rainfall intensity, the nature of the plant canopy and ...
Rebecca E. Campbell, D. Roger Wallis, Monika Walter   +2 more
doaj   +1 more source

DESIGN AND TESTING OF A SMALL ORCHARD TRACTOR DRIVEN BY A POWER BATTERY [PDF]

Engenharia Agrícola, 2023
An electric orchard tractor with a power battery and transmission driven by dual motors was developed. The output shafts of the walking and power take-off (PTO) motors are connected by a wet clutch, which controls whether the two motors are coupled or ...
Han Jiangyi, Wang Fan
doaj   +1 more source

Multilocus sequence typing (MLST) methods for the emerging Campylobacter species C. hyointestinalis, C. lanienae, C. sputorum, C. concisus and C. curvus

Frontiers in Cellular and Infection Microbiology, 2012
Multilocus sequence typing (MLST) systems have been reported previously for multiple food- and food animal-associated Campylobacter species (e.g. C. jejuni, C. coli, C. lari and C. fetus) to both differentiate strains and identify clonal lineages. These
William G Miller, Mary H Chapman, Emma eYee, Stephen L.W. On, Desmond K McNulty, Albert J Lastovica, Anne M Carroll, Eleanor B McNamara, Geraldine eDuffy, Robert E Mandrell   +9 more
doaj   +1 more source

A Life Cycle Cost Analysis—Relevant Method Supporting the Decision to Establish an Apple Orchard in an Organic System

Horticulturae, 2023
The life-cycle cost analysis is a method used to assess long-term economic efficiency among equivalent competing processes or products. The purpose of this paper is to investigate the nature and level of costs for an organic orchard located in Southern ...
Ionela Mițuko Vlad, Ana Cornelia Butcaru, Gina Fîntîneru, Liliana Aurelia Bădulescu, Florin Stănică, Cosmin Alexandru Mihai   +5 more
doaj   +1 more source