Results 111 to 120 of about 59,394 (312)

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

open access: yesAdvanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang   +10 more
wiley   +1 more source

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

open access: yesAdvanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu   +13 more
wiley   +1 more source

Annual concerto concert, April 12, 1987

open access: yes, 2016
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, April 12, 1987, 3:00 p.m., the 350th concert of the School of Music's 1986-1987 season.University Symphony Orchestra, Anthony Elliott, conductor ...
Western Michigan University. Symphony Orchestra
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Toledo Symphony Orchestra, compositions performed soloists heard, first season 1920-1921 with press comments

open access: yes, 2023
Program of the Toledo Symphony Orchestra, Toledo, Ohio, during the 1920-1921 season, detailing the compositions performed, soloists heard, and the press comments of the first ...
Toledo Symphony Orchestra
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ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

open access: yesAdvanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao   +16 more
wiley   +1 more source

University Symphony Orchestra, February 3, 1980

open access: yes, 2018
Recorded during a live performance at Miller Auditorium, Western Michigan University, February 3, 1980, program no. 179 of the Department of Music's 1979-1980 season.University Symphony Orchestra ; Herbert Butler, conductor ; Joseph Work, viola (2nd work)

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Toledo Symphony Orchestra season of 1920-21, third symphony program, January 12, 1921

open access: yes, 2023
Third program of the Toledo Symphony Orchestra, Toledo, Ohio, on January 12, 1921.
Toledo Symphony Orchestra
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GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

University Symphony Orchestra, November 26, 1996 : from modern to classic

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, November 26, 1996, 8:00 p.m., the 184th concert of the School of Music's 1996-1997 season.University Symphony Orchestra, Eric Shumsky ...
Western Michigan University. Symphony Orchestra
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Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

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