Results 241 to 250 of about 59,394 (312)

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

Tailored Catalytic Microenvironments Enable Efficient Electrochemical Ammonia Production

open access: yesAdvanced Science, EarlyView.
This study shows that Co2+ substitution in inverse spinel FeFeCoO4 constructs an integrated catalytic microenvironment for efficient nitrate‐to‐ammonia reduction. Jahn–Teller distortion activates Fe sites for *H generation, while hard–soft acid–base regulated dual‐metal sites optimize proton‐coupled electron transfer and intermediate adsorption ...
Qi Zhang   +8 more
wiley   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo   +13 more
wiley   +1 more source

Reality Check: The Aspirations of the European Health Data Space Amidst Challenges in Decentralized Data Analysis. [PDF]

open access: yesJ Med Internet Res
Fröhlich H   +9 more
europepmc   +1 more source

Firefighters' Expertise in Locating Sounds. [PDF]

open access: yesBrain Sci
Tissieres I   +2 more
europepmc   +1 more source

Risk of SARS-CoV-2 Reinfections Among Healthcare Workers of Four Large University Hospitals in Northern Italy: Results of an Online Survey Within the ORCHESTRA Project. [PDF]

open access: yesVaccines (Basel)
Liviero F   +15 more
europepmc   +1 more source

Musician presence and its effects on physiological and psychological well-being in live versus livestreamed concerts. [PDF]

open access: yesSci Rep
Becker AS   +9 more
europepmc   +1 more source

Birds in Flight. [PDF]

open access: yesMethodist Debakey Cardiovasc J
Alexander P.
europepmc   +1 more source

Home - About - Disclaimer - Privacy