Results 51 to 60 of about 59,394 (312)
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
University Symphony Orchestra, November 30, 1989
, 2016 Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, November 30, 1989, 8:00 p.m., the 120th concert of the School of Music’s 1989-1990 season.University Symphony Orchestra ; Richard J ...
Western Michigan University. Symphony Orchestra
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Томский академический симфонический оркестр: начало пути
Вестник музыкальной науки, 2019 Рассмотрены первые годы деятельности Томского академического симфонического оркестра, одного из первых симфонических оркестров в Западной Сибири, созданного в 1946 г.
Вавилов, Станислав Платонович +1 more
doaj +1 more source
Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar +3 more
wiley +1 more source
Orchestra concert, October 14, 1990
, 2016 Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, October 14, 1990, 3:00 p.m., the 40th concert of the School of Music’s 1990-1991 season.University Symphony Orchestra (1st-2nd, 4th works), Robert ...
Western Michigan University. Symphony Orchestra
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INSTRUMENTAL STUDY WITH SUPPORT OF THE MATERIALS E-ORCHESTRA [PDF]
Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2016 The advanced stage of studying a soloist instrument, involves mostly working with a pianist-accompanist or with an orchestra because the curriculum includes a compulsory study of some scores for solo instrument and orchestra, and most of them are oft en ...
DEMENESCU VERONICA-LAURA, ROMAN IULIA
doaj
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Spring session Chamber Orchestra, June 6, 1977
, 2018 Recorded during a live performance at Oakland Recital Hall, Western Michigan University, June 7, 1977, program no. 247 of the Department of Music's 1976-1977 season.Spring session Chamber Orchestra ; Herbert Butler, conductor ; Charles Osborne, flute ...
Western Michigan University. Chamber Orchestra
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