Results 231 to 240 of about 56,843 (293)

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

open access: yesAdvanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su   +7 more
wiley   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

open access: yesAdvanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten   +30 more
wiley   +1 more source

Leveraging technologies for data management and sharing to foster collaboration and implement data spaces. [PDF]

open access: yesData Brief
Chrysakis I   +9 more
europepmc   +1 more source

Toward Intelligent Rehabilitation Program Management: A System-Level Review of AI Architectures. [PDF]

open access: yesBioengineering (Basel)
Luca C   +5 more
europepmc   +1 more source

Towards a sustainable astronomical data infrastructure: Optimising linking data from the Rucio datalake to the users areas within the SKA Regional Centres Network. [PDF]

open access: yesOpen Res Eur
Parra-Royón M   +11 more
europepmc   +1 more source

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