Results 81 to 90 of about 453,816 (258)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Coulomb gluons and the ordering variable [PDF]
, 2015 We study in detail the exchange of a Coulomb (Glauber) gluon in the first few orders of QCD perturbation theory in order to shed light on their accounting to all orders. We find an elegant cancellation of graphs that imposes a precise ordering on the transverse momentum of the exchanged Coulomb gluon.
arxiv +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Protocols for Kak's Cubic Cipher and Diffie-Hellman Based Asymmetric Oblivious Key Exchange [PDF]
arXiv, 2006 This paper presents protocols for Kak's cubic transformation and proposes a modification to Diffie-Hellman key exchange protocol in order to achieve asymmetric oblivious exchange of keys.
arxiv
End-User Order Flow and Exchange Rate Dynamics [PDF]
SSRN Electronic Journal, 2007 In this paper we provide evidence for Evans and Lyons' (2005b) model of an information aggregation process in FX markets using a German bank's end-user order flow from 2002 to 2003. Though customer order flow is unambiguously the vehicle incorporating non-public information into exchange rates over time, our empirical analysis does not support the ...
Stefan Reitz +4 more
openaire +3 more sources
Radiotherapy medical physics in the Philippines: A contemporary overview
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose With cancer ranking as the third leading cause of death in the Philippines and a disparity in healthcare resources across regions, this research aimed to assess the state of radiotherapy medical physics in the country. Methodology The study utilized a comprehensive online survey with 94 structured questions answered by 19 clinics ...
John Paul C. Cabahug +4 more
wiley +1 more source
Orbital Dependent Exchange-Only Methods for Periodic Systems [PDF]
arXiv, 1999 Various orbital-dependent exchange-only potentials are studied which exhibit correct long-range asymptotic behaviour. We present the first application of these potentials for polymers and by one of these potentials for molecules. Kohn-Sham type calculations have been carried out for polyethylene in order to make valuable comparison of these potentials ...
arxiv
Wick Order, Spreadability and Exchangeability for Monotone Commutation Relations [PDF]
Annales Henri Poincaré, 2018 Ann.
Crismale, Vitonofrio +2 more
openaire +4 more sources
Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar +6 more
wiley +1 more source
Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett +8 more
wiley +1 more source