Results 141 to 150 of about 13,288,132 (297)
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
[Letter from the Order of Canada, 12 January 1973]
, 1973 A letter from the Order of Canada addressed to Mr. de Grandmaison and signed by Carl Lochnan, Director of Honors. The letter includes information about the Investiture of the Order held on April 11, 1973, at the Government House in ...
The Order of Canada
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Analysis of Flow Meters Calibration [PDF]
, 2015 Calibration data of flow meters are often reported using the so called calibration coefficient, i.e. the ratio between the reference flow rate (or equivalent quantity, e.g.
SPAZZINI, PIER GIORGIO +3 more
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Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Integrated Synthetic Platforms for Chemical Probes: A Journey through the Routes of Flow Processing
, 2017 The talk will focus on our recent efforts directed towards the design and implementation of integrated flow platforms for the production of chemical probes and compound library in drug discovery ...
Gioiello, A.
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The hydraulic and hydrological performance of large wood accumulation in a low-order forest stream
, 2010 Large wood and its accumulations are poorly understood despite being an important feature in the functioning of forested river channels and floodplains.
Kitts, Duncan Renfield
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FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Exchange Rates and Order Flow in the Long Run [PDF]
Several recent papers have underlined the importance of the microstructure effects in understanding exchange rate behavior by documenting stable long-run relationships between cumulated order flows and spot exchange rates.
M. Martin Boyer, Simon van Norden
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New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source