Results 71 to 80 of about 9,805,432 (298)

A note on generalized Genome Scan Meta-Analysis statistics

open access: yesBMC Bioinformatics, 2005
Background Wise et al. introduced a rank-based statistical technique for meta-analysis of genome scans, the Genome Scan Meta-Analysis (GSMA) method. Levinson et al.
Feng Anne C, Koziol James A
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

GIVE statistic for goodness of fit in instrumental variables models with application to COVID data

open access: yesScientific Reports, 2022
Since COVID-19 outbreak, scientists have been interested to know whether there is any impact of the Bacillus Calmette–Guerin (BCG) vaccine against COVID-19 mortality or not.
Subhra Sankar Dhar, Shalabh
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Ship Detection Algorithm Based on Spatially Variant Apodization Sidelobe Suppression and Order Statistic-Constant False Alarm Rate

open access: yesLeida xuebao, 2020
The special imaging mechanism of the Synthetic Aperture Radar (SAR) causes the sidelobe effect on SAR images. In target detection, the sidelobe effect changes the shapes of strong reflective targets, which results in the problems of localization ...
HUANG Yinli   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

An Inversion Statistic on the Hyperoctahedral Group [PDF]

open access: yes, 2023
In this paper, we introduce an inversion statistic on the hyperoctahedral group $B_n$ by using an decomposition of a positive root system of this reflection group. Then we prove some combinatorial properties for the inversion statistic.
Arslan, Hilal Karakus   +2 more
core   +1 more source

A model combining with statistic model and chaos-optimized extreme learning machine for dam deformation monitoring

open access: yesShuili Shuiyun Gongcheng Xuebao, 2016
Deformation is an important effect reflecting the dynamic evolution of a dam. In order to improve prediction precision of the statistic model,with the advantage of the extreme learning machine (ELM) to deal with the nonlinear problems,data mining for dam
DAI Bo, HE Qi
doaj   +1 more source

Admissibility when Estimating the Population Counterpart of a U-Statistic of Order 2 Employing a Pseudo Bayesian Argument [PDF]

open access: yesThe Egyptian Statistical Journal, 1998
In this paper, a pseudo Bayesian argument due to Basu (1971) is employed to construct an estimator for a class of parametric functions namely the population counterpart of a one sample U-statistic of order 2.
Reda Mazloum
doaj   +1 more source

Order Statistics and Statistics of Structure $(d)$

open access: yesThe Annals of Mathematical Statistics, 1965
This note discusses the asymptotic independence of the "$(d)$-structured" order statistics $F(X^{(i)})$ and some of the more usual statistics of structure $(d)$. (For a discussion of structure $(d)$ and related concepts, see references [2], [3] and [4].) Asymptotic independence holds, in particular, in the case of the Kolmogoroff-Smirnoff statistic ...
openaire   +2 more sources

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