Results 71 to 80 of about 270,694 (310)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

On order statistics from the Gompertz–Makeham distribution and the Lambert W function

open access: yesMathematical Modelling and Analysis, 2013
The aim of this paper is twofold. First, we show that the expected value of the minimum order statistic from the Gompertz-Makeham distribution can be expressed in closed form in terms of the incomplete gamma function.
Pedro Jodra
doaj   +1 more source

GIVE statistic for goodness of fit in instrumental variables models with application to COVID data

open access: yesScientific Reports, 2022
Since COVID-19 outbreak, scientists have been interested to know whether there is any impact of the Bacillus Calmette–Guerin (BCG) vaccine against COVID-19 mortality or not.
Subhra Sankar Dhar, Shalabh
doaj   +1 more source

The Generalized Odd Lindley-G Family: Properties and Applications

open access: yesAnais da Academia Brasileira de Ciências
: We introduce a new class of continuous distributions called the generalized odd Lindley-G family. Four special models of the new family are provided. Some explicit expressions for the quantile and generating functions, ordinary and incomplete moments ...
AHMED Z. AFIFY   +5 more
doaj   +1 more source

A note on generalized Genome Scan Meta-Analysis statistics

open access: yesBMC Bioinformatics, 2005
Background Wise et al. introduced a rank-based statistical technique for meta-analysis of genome scans, the Genome Scan Meta-Analysis (GSMA) method. Levinson et al.
Feng Anne C, Koziol James A
doaj   +1 more source

Ship Detection Algorithm Based on Spatially Variant Apodization Sidelobe Suppression and Order Statistic-Constant False Alarm Rate

open access: yesLeida xuebao, 2020
The special imaging mechanism of the Synthetic Aperture Radar (SAR) causes the sidelobe effect on SAR images. In target detection, the sidelobe effect changes the shapes of strong reflective targets, which results in the problems of localization ...
HUANG Yinli   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Admissibility when Estimating the Population Counterpart of a U-Statistic of Order 2 Employing a Pseudo Bayesian Argument [PDF]

open access: yesThe Egyptian Statistical Journal, 1998
In this paper, a pseudo Bayesian argument due to Basu (1971) is employed to construct an estimator for a class of parametric functions namely the population counterpart of a one sample U-statistic of order 2.
Reda Mazloum
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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