This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue +17 more
wiley +1 more source
Complexity and psychopathology: from mechanistic science to a physical understanding of the mental conditions based on chaos and complexity. [PDF]
Abramov DM.
europepmc +1 more source
Multi‐Tissue Genetic Regulation of RNA Editing in Pigs
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan +21 more
wiley +1 more source
Refining estimation techniques for the Two-Sided Power Distribution: A data-sensitive perspective. [PDF]
Güral Y.
europepmc +1 more source
Bioenergy Cropping Reduces the Spatiotemporal Scaling of Soil Bacterial Biodiversity
Consistent with patterns observed in plant and animal communities, soil bacterial communities exhibit significant species–time–area and phylogenetic–time–area relationships independent of nested structure. Bioenergy cropping significantly reduces the spatiotemporal scaling rates, particularly in sandy loam soils.
Zhencheng Ye +19 more
wiley +1 more source
A new family of alpha power-G using cosine function with applications and regression modeling. [PDF]
Alghamdi AS, ALoufi SF.
europepmc +1 more source
Direct Recycling of Mixed‐Oxide Cathodes: Balancing Cost, Performance and Environmental Trade‐Offs
Direct regeneration routes for mixed‐oxide lithium‐ion battery cathodes are systematically compared using harmonized techno‐economic, electrochemical, and environmental metrics. Solid‐state, hydrothermal, molten salt, electrochemical, and chemical relithiation methods are benchmarked to identify performance, cost, and sustainability trade‐offs.
Evgenii Beletskii +8 more
wiley +1 more source
Exploring a Dynamic Template Matching Algorithm for the Automatic Extraction of P3 Latencies. [PDF]
Lesche S +4 more
europepmc +1 more source
An Intelligent Magneto‐Mechanical Platform for Cellular Sensing in 3D Microenvironments
This study presents MagMI, a pioneering machine intelligence‐driven magneto‐mechanical sensing platform. It utilizes magneto‐mechanical arrays and machine learning to achieve label‐free, real‐time monitoring and classification of cellular proliferation dynamics within 3D microenvironments.
Yue Quan +4 more
wiley +1 more source
Inference and Visualization of Complex Genotype-Phenotype Maps. [PDF]
Martí-Gómez C +5 more
europepmc +1 more source

