Results 201 to 210 of about 813,474 (259)

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong   +14 more
wiley   +1 more source

Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model

open access: yesAdvanced Science, EarlyView.
Understanding protein sequence–function relationships remains challenging due to poorly defined motifs and limited residue‐level annotations. An annotation‐agnostic framework is introduced that segments protein sequences into “protein words” using attention patterns from protein language models.
Hedi Chen   +9 more
wiley   +1 more source

Highly Sensitive Heterojunction‐Gated Phototransistor With Detection Wavelength Ranged From 350 to 1700 Nm

open access: yesAdvanced Science, EarlyView.
This work demonstrates a heterojunction‐gated infrared phototransistor for broadband detection from 350 to 1700 nm. By suppressing defect states on nonpolar (100) facets of large PbS quantum dots via hybrid ligand passivation, the device achieves a room‐temperature detectivity of 5.7 × 1013 Jones at 1650 nm.
Hongkun Duan   +14 more
wiley   +1 more source

A flexible extension of the log-logistic model with diverse failure rate shapes and applications. [PDF]

open access: yesSci Rep
Afify AZ   +5 more
europepmc   +1 more source

How AI Shapes the Future Landscape of Sustainable Building Design With Climate Change Challenges?

open access: yesAdvanced Science, EarlyView.
This review examines how artificial intelligence reshapes sustainable building design faced with climate change challenges. The authors synthesize existing studies to demonstrate AI's transformative potential across design lifecycle phases from climate‐aware form generation to performance optimization.
Pengyuan Shen   +5 more
wiley   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

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