Results 91 to 100 of about 384,528 (314)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Completion of a half linearly cyclically ordered group
, 2002 The notion of a half lc-group G is a generalization of the notion of a half linearly ordered group. A completion of G by means of Dedekind cuts in linearly ordered sets and applying Świerczkowski's representation theorem of lc-groups is constructed and ...
Černák, Štefan
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Carboxylic group functionalized ordered mesoporous silicas
, 2011 Many research efforts have focused on the synthesis of organic and inorganic hybrid ordered mesoporous silicas (MSs) with functionalization of the exterior and/or interior surfaces aiming for applications in separation, adsorption, catalysis, drug ...
Che, Shunai +5 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
On the Riesz structures of a lattice ordered abelian group
, 2019 A Riesz structure on a lattice ordered abelian group G is a real vector space structure where the product of a positive element of G and a positive real is positive. In this paper we show that for every cardinal k there is a totally ordered abelian group
Lenzi, Giacomo
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Data extraction table for occupation studies (ordered by occupational group).
, 2013 Data extraction table for occupation studies (ordered by occupational group).
Simon Wessely (354884) +5 more
core +1 more source