Results 161 to 170 of about 1,425,221 (328)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
, 1997 The notion of a Hosszú-Gluskin algebra \((Q,\{\cdot,\varphi,b\})\) of order \(n\geq 3\) (briefly \(n\)HG-algebra) and of the \(n\)HG-algebra associated to an \(n\)-group \((Q,A)\) is given. The following theorem is proved: Let \((Q,\{\cdot,\varphi,b\})\) be an arbitrary \(n\)HG-algebra associated to the \(n\)-group \((Q,A)\) (\(n\geq 3\)).
Usan, J., Zizovic, M.
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
International Journal of Nanomedicine, 2018 Daijun Zhou, Tao Yang, Wei Qian, Malcolm Xing, Gaoxing Luo Institute of Burn Research; State Key Laboratory of Trauma, Burn and Combined Injury; Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China Objective:
Zhou D, Yang T, Qian W, Xing M, Luo G
doaj
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Toeplitz algebras on discrete abelian quasily ordered groups [PDF]
, 1999 Qingxiang Xu
openalex +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
A model-assisted design for partially or completely ordered groups. [PDF]
Pharm StatCelum C, Conaway M.
europepmc +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source