Results 141 to 150 of about 4,040,795 (295)
Priestley-type dualities for partially ordered structures
, 2016 We introduce a general framework for generating dualities between categories of partial orders and categories of ordered Stone spaces; we recover in particular the classical Priestley duality for distributive lattices and establish several other ...
CARAMELLO, OLIVIA
core +1 more source
Fabrication of 3D Ordered Structures with Multiple Materials via Macroscopic Supramolecular Assembly. [PDF]
Adv Sci (Weinh), 2020 Zhang Q, Sun Y, He C, Shi F, Cheng M.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
An Overview of Methods in the Analysis of Dependent ordered catagorical Data: Assumptions and Implications [PDF]
Subjective assessments of pain, quality of life, ability etc. measured by rating scales and questionnaires are common in clinical research. The resulting responses are categorical with an ordered structure and the statistical methods must take account of
Högberg, Hans, Svensson, Elisabeth
core
Small StructuresIn this article, the results of a combined experimental and theoretical investigation which provides evidence of the existence of large well‐ordered structures of helium atoms in HeNHo2+ and HeNBi2+ clusters.
Florian Foitzik +10 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source