Results 51 to 60 of about 312,213 (278)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Post-processing of Deep Web Information Extraction Based on Domain Ontology
Advances in Electrical and Computer Engineering, 2013 Many methods are utilized to extract and process query results in deep Web, which rely on the different structures of Web pages and various designing modes of databases. However, some semantic meanings and relations are ignored.
PENG, T., LIU, L.
doaj +1 more source
Bands in partially ordered vector spaces with order unit [PDF]
, 2014 In an Archimedean directed partially ordered vector space X, one can define the concept of a band in terms of disjointness. Bands can be studied by using a vector lattice cover Y of X.
A. Kalauch, Bas Lemmens, O. Gaans
semanticscholar +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Order convergence of vector measures on topological spaces [PDF]
Mathematica Bohemica, 2008 Summary: Let \(X\) be a completely regular Hausdorff space, \(E\) a boundedly complete vector lattice, \(C_{b}(X)\) the space of all, bounded, real-valued continuous functions on \(X\), \(\mathcal {F}\) the algebra generated by the zero-sets of \(X\), and \(\mu \: C_{b}(X) \to E\) a positive linear map.
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Infinitesimals in ordered vector spaces
Владикавказский математический журнал, 2013 An infinitesimal approach to ordered spaces is proposed. Archimedean property and Dedekind completeness in ordered spaces are discussed from a nonstandard point of view.
openaire +2 more sources
Shape preserving approximation in vector ordered spaces
Applied Mathematics Letters, 2005 AbstractThe aim of this note is to extend some classical results on the shape preserving approximation of real functions (of real variables) to functions with values in ordered vector spaces.
George A. Anastassiou, Sorin G. Gal
openaire +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source