Machine learning‐assisted clone selection for intensified cell culture processes
Abstract Intensified fed‐batch processes are becoming increasingly prevalent among biomanufacturers due to their superior space–time yields relative to traditional, non‐intensified fed‐batch processes. However, the shift towards intensified manufacturing has unexpectedly made optimal clone selection more challenging.
Nicolas Wolnick +6 more
wiley +1 more source
Beyond ordinal scales: making animal welfare count in policy analysis. [PDF]
Fischer B.
europepmc +1 more source
ABSTRACT Limited access to cadavers necessitates the availability of digital resources for anatomy education. Smartphone‐based photogrammetry offers a promising solution for creating three‐dimensional (3D) and augmented reality (AR) models. This study compared two mobile photogrammetry applications (Qlone and Polycam) that have been used in modern ...
Sarita Phukwantong +3 more
wiley +1 more source
Numerical cognition in speakers of an Amazonian language with exactly twenty number words. [PDF]
da Silva Sinha V +3 more
europepmc +1 more source
A goodness‐of‐fit test for regression models with discrete outcomes
Abstract Regression models are often used to analyze discrete outcomes, but classical goodness‐of‐fit tests such as those based on the deviance or Pearson's statistic can be misleading or have little power in this context. To address this issue, we propose a new test, inspired by the work of Czado et al.
Lu Yang +2 more
wiley +1 more source
Wheat Soil-Borne Mosaic Virus Disease Detection: A Perspective of Agricultural Decision-Making via Spectral Clustering and Multi-Indicator Feedback. [PDF]
Hou X +7 more
europepmc +1 more source
CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park +2 more
wiley +1 more source
Sex Differences in Prognostic Markers: Exploring Outcome Variability After Mechanical Thrombectomy in Large Vessel Occlusion Stroke. [PDF]
Schacht H +10 more
europepmc +1 more source
Statin‐associated muscle symptoms (SAMS) are frequent adverse effects of statin therapy and have been hypothesized to result from impaired coenzyme Q10 (CoQ10) biosynthesis. Although genetic determinants of CoQ10 levels have been reported, genome‐wide association studies (GWASs) conducted specifically in statin users are lacking. Moreover, direct CoQ10
Da Hoon Lee +6 more
wiley +1 more source
Safety and feasibility of cerebrolysin in treatment of primary intracerebral hemorrhage (CLINCH)-a prospective, randomized, open-label, blinded endpoint pilot trial. [PDF]
Kobayashi A +5 more
europepmc +1 more source

