Results 151 to 160 of about 526,028 (331)

Mother–Child Biobehavioral Synchrony and Its Association With Social Functioning in Autistic School‐Aged Children

open access: yesAutism Research, EarlyView.
ABSTRACT Parent–child biobehavioral synchrony, or the concordance of behavior and physiological indicators between individuals, is theorized to support children's social development; however, this relationship has yet to be investigated in autistic children.
Carly Moser   +5 more
wiley   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet   +17 more
wiley   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel   +12 more
wiley   +1 more source

Consensus with ordinal data

open access: yes, 1999
We present a model allowing to aggregate decision criteria when the available information is of qualitative nature. The use of the Sugeno integral in this model is justified by an axiomatic approach. An illustrative example is also provided.
Marichal, Jean-Luc, Roubens, Marc
openaire   +1 more source

Community pharmacists' practices and perspectives on deprescribing high‐risk psychotropic medicines: National survey findings

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To explore the practices, confidence and perspectives of community pharmacists in deprescribing high‐risk psychotropic medicines, including opioid analgesics, benzodiazepine, gabapentinoids and medicinal cannabis. Methods An anonymous, cross‐sectional national online survey was conducted between January and April 2025 among Australian community ...
Monica Jung   +5 more
wiley   +1 more source

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