Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Characterization of the five-tier model of creative mathematical thinking in primary school learners
Creative mathematical thinking skills among elementary students remain relatively low, largely due to predominantly procedural instruction, highlighting the need to examine the characteristics of their innovative thinking stages in solving data ...
Ervita Tri Susilowati +2 more
doaj +1 more source
Comparative analysis for quantification of Citrus Variegated Chlorosis in the field
Citrus Variegated Chlorosis (CVC) caused by Xylella fastidiosa is one of the most important diseases for Brazilian citriculture. The CVC is a vascular disease with a long incubation period and symptoms similar to other disorders, and this factors ...
Fabrício Packer Gonçalves +4 more
doaj +1 more source
Ordinal imbalanced datasets are pervasive in real world applications but remain challenging to analyse as they require specific methods to account for the ordering information and imbalanced classes.
Marine Desprez, Kyle Zawada, Daniel Ramp
doaj +1 more source
mgee2: An R package for marginal analysis of longitudinal ordinal data with misclassified responses and covariates [PDF]
Yuliang Xu, Shuo Liu Shuo, Y. Yi Grace
openalex +1 more source
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
Identifying Biomarkers from Mass Spectrometry Data with Ordinal Outcome
In recent years, there has been an increased interest in using protein mass spectroscopy to identify molecular markers that discriminate diseased from healthy individuals.
Deukwoo Kwon +4 more
doaj +2 more sources
Knee Crepitus and Osteoarthritis Features in Young Adults Following Traumatic Knee Injury
Objective This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self‐reported outcomes in young adults following traumatic knee injury. Methods One year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years ...
Jamon L. Couch +8 more
wiley +1 more source
ICO, un indice de la consistance ordinale d’une série statistique [PDF]
Une série numérique générée à partir d’un processus séquentiel montre-t-elle une tendance identifiable (monotonicité partielle ou complète), un désordre excessif, ou une simple variance d’erreur?
Laurencelle, Louis
doaj +1 more source

