Results 131 to 140 of about 134,556 (286)

A phase 3, randomized clinical trial of soticlestat as adjunctive therapy for Lennox–Gastaut syndrome

Epilepsia, EarlyView.
Soticlestat as adjunctive therapy for Lennox–Gastaut syndrome. Abstract Objective There remains a need for new treatments for Lennox–Gastaut syndrome (LGS), a developmental and epileptic encephalopathy with a heterogenous patient population that often requires polytherapy. The phase 3, randomized SKYWAY study (NCT04938427) investigated the efficacy and
Renzo Guerrini, Eric D. Marsh, Wei‐Ping Liao, Katsumi Imai, Ruzica Kravljanac, Anna Altmann, Cecil D. Hahn, Stéphane Auvin, Jimmy Schiemann, Yasir Khan, Pranab Mitra, Sarah I. Sheikh, Philipp von Rosenstiel, Mahnaz Asgharnejad, Dennis Dlugos, Venkatesha Murthy   +15 more
wiley   +1 more source

Epilepsy in emerging adulthood: Clinical, psychosocial, and surgical challenges

Epilepsia, EarlyView.
Abstract Objective Emerging adulthood (EAs; ages 19–29 years) is a unique developmental stage marked by major psychological, social, and occupational transitions. We sought to characterize the clinical, psychosocial, and surgical features of epilepsy in emerging adulthood, considering both current age and age at epilepsy onset.
Graham A. McLeod, Colin B. Josephson, Samuel Wiebe, The Calgary Comprehensive Epilepsy Program Collaborators, Felippe Borlot, Guillermo Delgado‐García, Paolo Federico, Nathalie Jette, Karl Martin Klein, William Murphy, Neelan Pillay, Andrea Salmon, Shaily Singh, The Epilepsy Surgery Satisfaction Questionnaire Study Group, Mark J. Atkinson, Walter J. Hader, Mark R. Keezer, Oluwaseyi A. Lawal, Sophia Macrodimitris, Kristina Malmgren, Dang K. Nguyen, Scott B. Patten, Tolulope T. Sajobi, Ruby Sharma, Yves Starreveld, José Tellez‐Zenteno, Sandra Wahby   +26 more
wiley   +1 more source

Robust estimation for ordinal regression. [PDF]

Ordinal regression is used for modelling an ordinal response variable as a function of some explanatory variables. The classical technique for estimating the unknown parameters of this model is Maximum Likelihood (ML).
Croux, Christophe, Haesbroeck, G., Ruwet, C.   +2 more
core  

Mental health of children with epilepsy in Ukraine during the war

Epilepsia, EarlyView.
Abstract Objective The ongoing conflict in Ukraine has created a severe humanitarian crisis, disproportionately affecting vulnerable populations such as children with chronic conditions. We set out to determine information about mental health in children with epilepsy in Ukraine affected by the conflict.
Volodymyr Kharytonov, J. Helen Cross, Andriy Dubenko, Samuel Wiebe, on behalf of the ILAE Emergency Task Force for Ukraine   +4 more
wiley   +1 more source

Prediction of treatment response in infantile epileptic spasms syndrome using EEG phase–amplitude coupling

Epilepsia Open, EarlyView.
Abstract Objective Treatment selection for infantile epileptic spasms syndrome (IESS) is complex and multifaceted, and currently no electroencephalogram (EEG) biomarkers can guide this decision by predicting treatment response. We tested the predictive value of phase–amplitude coupling (PAC) as IESS patients are known to have elevated PAC.
Soudeh Mostaghimi, Marco A. Pinto‐Orellana, Nathaniel Green, Daniel W. Shrey, Makoto Miyakoshi, Shaun A. Hussain, Beth A. Lopour   +6 more
wiley   +1 more source

Direct and Spatial Effects of Carbon Emission Trading System on Carbon Emissions in the Logistics Sector—Evidence From the Yangtze River Economic Belt in China

Energy Science &Engineering, EarlyView.
(1) A theoretical framework for examining the impact of the CETS on carbon emissions in the LS of the YREB is developed based on Porter's hypothesis and synergy theory. (2) Assessing the Effects of a CETS through DID Modeling. (3) The spatial correlation of carbon emissions within the LS is examined through the development of a SDM.
Zhaoyang Zhao, Chong Ye, Jing Huang
wiley   +1 more source

Patient‐ and caregiver‐reported barriers to radiotherapy for cancer in sub‐Saharan Africa—A survey of population‐based registries

International Journal of Cancer, EarlyView.
What's New? Low‐ and middle‐income countries have over 70% of the global cancer burden but 10% of the world's radiotherapy capacities. This population‐based multi‐country study explores the barriers to access experienced by cancer patients in sub‐Saharan Africa.
Eric Sven Kroeber, Tamara König, Ole Stöter, Biying Liu, Phoebe Mary Amulen, Margaret Borok, Gladys Chesumbai, Eric Chokunonga, Ima‐Obong Ekanem, Mahine Ivanga, Bakarou Kamaté, William Muller, Abidemi Omonisi, Jean‐Félix Peko, Mathewos Assefa, Furaha Serventi, Markus Wallwiener, Mazvita Muchengeti, Pablo Sandro Carvalho Santos, Donald Maxwell Parkin, Eva Johanna Kantelhardt, Nikolaus Christian Simon Mezger   +21 more
wiley   +1 more source

Health status analysis of blood donors: based on the ordinal multinomial logistic regression model

Zhongguo shuxue zazhi
[Objective] To explore the characteristics of lifestyle behaviors and mental health status among blood donors in Guangzhou, and to investigate the correlation between donation frequency and these factors.
FENG Fanfan, XIE Guiyun, DENG Xuecheng, OUYANG Jian, CHEN Chong, HONG Xiaochun, ZENG Sihai, ZHANG Yue, HUANG Manyu, CHEN Jinyan, RONG Xia, LI Shijie   +11 more
doaj   +1 more source

Identifying factors associated with child malnutrition in Ghana: a cross-sectional study using Bayesian multilevel ordinal logistic regression approach. [PDF]

BMJ Open, 2023
Iddrisu WA, Gyabaah O.
europepmc   +1 more source

The role of fetal viability in perineal and anal sphincter injury: Insights from a large cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Perineal injury is a common complication of vaginal delivery with implications for maternal morbidity. Injuries range from minor lacerations to severe obstetric anal sphincter injuries (OASI). The role of fetal viability in perineal outcomes remains unclear.
Daniel Gabbai, Emmanuel Attali, Itamar Gilboa, Ronen Gold, Asnat Groutz, Yariv Yogev, Yoav Baruch   +6 more
wiley   +1 more source