Results 171 to 180 of about 34,296 (312)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

[News Clip: Railroad ordinance]

, 1966
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Criminal Procedure Ordinance (Cap 221)

, 2019
This Criminal Law & Procedure Handbook aims to make available, in a convenient and up-to-date form, the consolidated text of the Crimes Ordinance (Cap 200), Criminal Procedure Ordinance (Cap 221), Dangerous Drugs Ordinance (Cap 134), Juvenile Offenders ...
Andra le Roux-Kemp (17161918)
core   +1 more source

Small Animal Veterinarians' Perceptions and Practices in Dog Aggression Prevention in Italy: A National Survey. [PDF]

Animals (Basel)
Iarussi F, Milelli V, Di Gesù F, Colella A, Recchia A, D'Ingeo S.   +5 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Traffic Ordinance

, 1916
Traffic Ordinance. An Ordinance regulating traffic and travel upon the public streets of the city of Albuquerque.
Mayor Henry Westerfeld
core  

Impact of explicit fluoride-related language in prefectural dental health ordinance on fluoride mouth-rinse programs dissemination in Japan: a quasi-experimental study. [PDF]

Front Oral Health
Hoshi-Harada M, Taguchi C, Ishizuka Y, Ishiguro A, Matsuyama Y, Aida J, Osaka K, Takeuchi K.   +7 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

[News Clip: Ordinance violation]

, 1958
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about Addick Marlowe, the father of the boy who threw a firecracker bomb at L.E.
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Semantic clause retrieval for trademark law using transformer encoders and lexical baselines: a cross-domain agri-robotics compliance case study. [PDF]

Sci Rep
Asfand E Yar M, Hashir Q, Tanveer MH, Voicu RC, Khalid A.   +4 more
europepmc   +1 more source