Results 261 to 270 of about 34,296 (312)

Mental health policy interventions in Nigeria: A scoping review of development, implementation and outcomes. [PDF]

Glob Ment Health (Camb)
Damul B, King HC, Jafiya H, Bestman C.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

"We're building the plane while we're flying it": perspectives on local cigar policy implementation from qualitative interviews with key personnel. [PDF]

Implement Sci Commun
Jensen JK, LaCapria K, Gratale S, Macenat M, Ferrante JM, Williams AM, Asberom H, Delnevo CD, Azagba S.   +8 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Intraoperative endoscopic pylorus dilatation during minimally invasive <i>Ivor Lewis</i> oesophagectomy to prevent delayed gastric conduit emptying (DGCE): protocol for the WIDE randomised controlled trial. [PDF]

BMJ Open
Cron L, Klasen JM, Neuschütz K, Dirnberger A, Maaser A, Baur J, Heinrich H, Gockel I, Bolli M, Müller BP, Kraljević M.   +10 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

The status of interprofessional medical and nursing education in wound care at German higher education institutions. [PDF]

GMS J Med Educ
Weiß A, Richters C, Kiriakidou R, Hausen A, Fischer MR, Stadler M, Witti MJ.   +6 more
europepmc   +1 more source

Negative health outcomes of non-response to the Kihon checklist in community-dwelling older people: a 19-month prospective cohort study. [PDF]

BMC Geriatr
Kazawa K, Moriyama M, Sato K, Ishii S.
europepmc   +1 more source

Fair Workweek laws in the US: An appraisal of intended and unintended consequences. [PDF]

Sci Adv
Schneider D, Harknett K, Arbelaez D.
europepmc   +1 more source

Child and adolescent mental health burden, policies, and services in high-income countries and areas in the Western Pacific Region. [PDF]

Lancet Reg Health West Pac
Hung YA, Choi M, Liao YA, Bowden M, Ong SH, Hwang TY, Kakimoto M, Ni MY, Nishio A, Garcia-Quiroga J, Wong CSM, Lu C, Chang SS.   +12 more
europepmc   +1 more source