Results 81 to 90 of about 281,065 (293)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Refinement of Cadastral Maps [PDF]

open access: yesActa Montanistica Slovaca, 2011
The amended cadastral ordinance takes effect from 1.7. 2009. Until this date the only cadastral maps for which two listsof coordinates for detailed survey points were filed were digitalized cadastral maps in stable cadastre coordinate systems.
Alena Berková
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Seeding the City: Land Use Policies to Promote Urban Agriculture [PDF]

open access: yes, 2011
Outlines the health, environmental, and economic benefits of urban agriculture; considerations for developing relevant land use policy; legal tools for preserving plots, and other laws.

core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Implications of Densification Policies for Greater Resistencia (Argentina): an Assessment of Recent Experience [PDF]

open access: yes, 2014
. Since 2001, Resistencia City Council has been promoting growth in building height by steering development towards built-up areas in central districts that already have complete infrastructure, through the implementation of the Ordinance 5403/01 - high ...
Schneider, V. (Valeria)
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

City Rights in an Era of Preemption: A State-by-State Analysis [PDF]

open access: yes, 2017
In a new report, NLC finds that states limit city power through preemption in a number of policy areas, ranging from labor protections to taxing authority.Preemption is the use of state law to nullify a municipal ordinance or authority.
Angelina Panettieri   +4 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Urban Water Quality and Fertilizer Ordinances: Avoiding Unintended Consequences: A Review of the Scientific Literature

open access: yesEDIS, 2009
SL-283, a 31-page illustrated fact sheet by George Hochmuth, Terril Nell, Jerry Sartain, J. Bryan Unruh, Chris Martinez, Laurie Trenholm, and John Cisar, discusses the research behind turfgrass growth, biology and ecology, and soil nutrient cycling in ...
George Hochmuth   +6 more
doaj   +1 more source

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