Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Bifurcation of multi-bump homoclinics in systems with normal and slow variables
Electronic Journal of Differential Equations, 2000 Bifurcation of multi-bump homoclinics is studied for a pair of ordinary differential equations with periodic perturbations when the first unperturbed equation has a manifold of homoclinic solutions and the second unperturbed equation is vanishing.
Michal Feckan
doaj
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
An existence theorem in the algebraic study of homogeneous linear ordinary differential equations [PDF]
, 1955 M. P. Epstein
openalex +2 more sources
Existence of periodic solutions for a semilinear ordinary differential equation
Electronic Journal of Differential Equations, 1998 Dancer [3] found a necessary and sufficient condition for the existence of periodic solutions to the equation $$ ddot x +g_1(dot x) + g_0(x) = f(t),.$$ His condition is based on a functional that depends on the solution to the above equation with $g_0=0$.
Petr Girg
doaj
Reverse engineering gene regulatory network based on complex-valued ordinary differential equation model. [PDF]
BMC Bioinformatics, 2021 Yang B +6 more
europepmc +1 more source
Properties of solutions of an infinite system of ordinary linear differential equations of the first order with auxiliary boundary conditions [PDF]
, 1930 William T. Reid
openalex +1 more source
FEBS Open Bio, EarlyView.Method for Frailty Score (FS) calculation: (1) Combine all animals that will be compared in one group; (2) Calculate 20% cutoff; (3) Determine the number of animals that ‘failed’ or ‘passed’; (4) Calculate ‘percentage of success’ for graphical representation of parameters; (5) Repeat for all parameters; (6) Calculate FS and use percentages for ...
Aleksandra Mladenovic, Smilja Pracer
wiley +1 more source
Semiparametric Mixed-Effects Ordinary Differential Equation Models with Heavy-Tailed Distributions. [PDF]
J Agric Biol Environ Stat, 2021 Liu B, Wang L, Nie Y, Cao J.
europepmc +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source