Tailored parameter optimization methods for ordinary differential equation models with steady-state constraints. [PDF]
BMC Syst Biol, 2016 Fiedler A +4 more
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Parameter estimation and forecasting with quantified uncertainty for ordinary differential equation models using QuantDiffForecast: A MATLAB toolbox and tutorial. [PDF]
Stat MedChowell G, Bleichrodt A, Luo R.
europepmc +1 more source
A Comparison of Two-Stage Approaches for Fitting Nonlinear Ordinary Differential Equation Models with Mixed Effects. [PDF]
Multivariate Behav Res, 2016 Chow SM, Bendezú JJ, Cole PM, Ram N.
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk +7 more
wiley +1 more source
Customized Steady-State Constraints for Parameter Estimation in Non-Linear Ordinary Differential Equation Models. [PDF]
Front Cell Dev Biol, 2016 Rosenblatt M, Timmer J, Kaschek D.
europepmc +1 more source
Chebyshev Methods for Ordinary Differential Equations [PDF]
The Computer Journal, 1962 openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok +7 more
wiley +1 more source
A Bayesian approach to estimating hidden variables as well as missing and wrong molecular interactions in ordinary differential equation-based mathematical models. [PDF]
J R Soc Interface, 2017 Engelhardt B, Kschischo M, Fröhlich H.
europepmc +1 more source
Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham +14 more
wiley +1 more source