Results 261 to 270 of about 905,221 (366)

Comprehensive clinical evaluation of novel 4DCT‐based lung function imaging methods

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Methods have been developed that apply image processing to 4DCTs to generate 4DCT‐ventilation/perfusion lung imaging. Traditional methods for 4DCT‐ventilation rely on Hounsfield‐Unit (HU) density‐change methods and suffer from poor numerical robustness while not providing 4DCT‐perfusion data.
Ehsan Golkar   +6 more
wiley   +1 more source

Open‐source deep‐learning models for segmentation of normal structures for prostatic and gynecological high‐dose‐rate brachytherapy: Comparison of architectures

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The use of deep learning‐based auto‐contouring algorithms in various treatment planning services is increasingly common. There is a notable deficit of commercially or publicly available models trained on large or diverse datasets containing high‐dose‐rate (HDR) brachytherapy treatment scans, leading to poor performance on images ...
Andrew J. Krupien   +8 more
wiley   +1 more source

An extension to the OVH concept for knowledge‐based dose volume histogram prediction in lung tumor volumetric‐modulated arc therapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Volumetric‐modulated arc therapy (VMAT) treatment planning allows a compromise between a sufficient coverage of the planning target volume (PTV) and a simultaneous sparing of organs‐at‐risk (OARs). Particularly in the case of lung tumors, deciding whether it is possible or worth spending more time on further improvements of a treatment
Johann Brand   +4 more
wiley   +1 more source

Design and validation of a novel dosimetry phantom for motion management audits

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background We present a novel phantom design for conducting end‐to‐end dosimetry audits for respiratory motion management of two anatomical treatment sites. The design enables radiochromic film measurements of the dose administered to the target throughout the respiratory cycle (motion‐included) and the dose delivered to the time‐averaged ...
Alex Burton   +5 more
wiley   +1 more source

A Python package for fast GPU‐based proton pencil beam dose calculation

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Open‐source GPU‐based Monte Carlo (MC) proton dose calculation algorithms provide high speed and unparalleled accuracy but can be complex to integrate with new applications and remain slower than GPU‐based pencil beam (PB) methods, which sacrifice some physical accuracy for sub‐second plan calculation.
Mahasweta Bhattacharya   +4 more
wiley   +1 more source

Improving dose delivery in non‐coplanar cranial SRS: Stereoscopic x‐ray‐guided mitigation of table walkout errors

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Purpose Linear accelerator (LINAC)‐based single‐isocenter multi‐target (SIMT) treatment has streamlined the cranial stereotactic radiosurgery (SRS) workflow. Though efficient, SIMT delivery adds additional challenges that should be considered, including increased sensitivity to rotational errors for off‐isocenter targets.
Yohan A. Walter   +4 more
wiley   +1 more source

Machine stability and dosimetry for ultra‐high dose rate FLASH radiotherapy human clinical protocol

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The FLASH effect, induced by ultra‐high dose rate (UHDR) irradiations, offers the potential to spare normal tissue while effectively treating tumors. It is important to achieve precise and accurate dose delivery and to establish reliable detector systems, particularly for clinical trials needed to help the clinical transfer of FLASH‐
Patrik Gonçalves Jorge   +9 more
wiley   +1 more source

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