CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Ordinary differential equations and their exponentials
Open Mathematics, 2006 Kock Anders, Reyes Gonzalo
doaj +1 more source
Analogue modelling an array of the FitzHugh–Nagumo oscillators
Nonlinear Analysis, 2012 The purpose of the paper is to show that analogue electronic modelling is an extremely fast technique compared to conventional digital computing, especially when solving large sets of coupled nonlinear differential equations.
Elena Tamaševičiūtė +1 more
doaj
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Data-driven anisotropic finite viscoelasticity using neural ordinary differential equations. [PDF]
Comput Methods Appl Mech Eng, 2023 Taç V +3 more
europepmc +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Forecasting virus outbreaks with social media data via neural ordinary differential equations. [PDF]
Sci Rep, 2023 Núñez M +3 more
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Geometry Splitting of Nonlinear Systems of Differential Equations Inti Blocks [PDF]
Both in theory and in many practical issues, a crucial role is played by the problem of solving systems of ordinary differential equations. One of these problems is the decomposition of the system of equations in blocks, i.e. in such a subsystem, each of
Kovancovs, Aleksandrs
core
Hazard-based distributional regression via ordinary differential equations. [PDF]
Stat Methods Med ResA Christen J, J Rubio F.
europepmc +1 more source