Results 31 to 40 of about 12,002 (244)

Linearized Stability Analysis of Nonlinear Delay Differential Equations with Impulses

open access: yesAxioms
This paper explores the linearized stability of nonlinear delay differential equations (DDEs) with impulses. The classical results on the existence of periodic solutions are extended from ordinary differential equations (ODEs) to DDEs with impulses ...
Mostafa Bachar
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Inference in complex biological systems with Gaussian processes and parallel tempering [PDF]

open access: yes, 2013
Parameter inference in mathematical models of complex biological systems, expressed as coupled ordinary differential equations (ODEs), is a challenging problem.
Dondelinger, F.   +2 more
core  

Domain formation in transitions with noise and time-dependent bifurcation parameter

open access: yes, 1996
The characteristic size for spatial structure, that emerges when the bifurcation parameter in model partial differential equations is slowly increased through its critical value, depends logarithmically on the size of added noise.
Lythe, G. D.
core   +1 more source

A Boundary Value Problem for a System of Ordinary Differential Equations with Impulse Effects

open access: yesRocky Mountain Journal of Mathematics, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Eloe, Paul W., Henderson, Johnny
openaire   +3 more sources

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller   +6 more
wiley   +1 more source

Peano Theorems for Pedjeu–Ladde-Type Multi-Time Scale Stochastic Differential Equations Driven by Fractional Noises

open access: yesMathematics
This paper examines fractional multi-time scale stochastic functional differential equations that, in addition, are driven by fractional noises. Based on a specially crafted fixed-point principle for the so-called “local operators”, we prove a Peano-type
Arcady Ponosov, Lev Idels
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Periodic solutions for ordinary differential equations with sublinear impulsive effects

open access: yesJournal of Mathematical Analysis and Applications, 2005
The authors investigate the existence of periodic solutions for ordinary differential equations with sublinear impulsive effects.
Qian, Dingbian, Li, Xinyu
openaire   +1 more source

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