Results 111 to 120 of about 5,984 (300)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Existence of periodic traveling wave solutions to the generalized forced Boussinesq equation

International Journal of Mathematics and Mathematical Sciences, 1999
The generalized forced Boussinesq equation, utt−uxx+[f(u)]xx+uxxxx=h0, and its periodic traveling wave solutions are considered. Using the transform z=x−ωt, the equation is converted to a nonlinear ordinary differential equation with periodic boundary ...
Kenneth L. Jones, Yunkai Chen
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Commutative Algebras of Ordinary Differential Operators with Matrix Coefficients

, 1996
A classification of commutative integral domains consisting of ordinary differential operators with matrix coefficients is established in terms of morphisms between algebraic ...
Kimura, Masato, Mulase, Motohico
core  

Linear Operators and the General Solution of Elementary Linear Ordinary Differential Equations

, 2012
We make use of linear operators to derive the formulae for the general solution of elementary linear scalar ordinary differential equations of order n. The key lies in the factorization of the linear operators in terms of first-order operators.
Euler, Norbert,, Euler, Norbert
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Nonclassical Sturm-Liouville problems and Schrodinger operators on radial trees

Electronic Journal of Differential Equations, 2000
Schrodinger operators on graphs with weighted edges may be defined using possibly infinite systems of ordinary differential operators. This work mainly considers radial trees, whose branching and edge lengths depend only on the distance from the root ...
Robert Carlson
doaj  

Relative boundedness and compactness theory for second-order differential operators

Journal of Inequalities and Applications, 1997
The problem considered is to give necessary and sufficient conditions for perturbations of a second-order ordinary differential operator to be either relatively bounded or relatively compact. Such conditions are found for three classes of operators. The
Don B. Hinton, Terry G. Anderson
doaj   +1 more source

Symmetric Division of Linear Ordinary Differential Operators

CoRR
The symmetric product of two ordinary linear differential operators $L_1,L_2$ is an operator whose solution set contains the product $f_1f_2$ of any solution $f_1$ of $L_1$ and any solution $f_2$ of~$L_2$. It is well known how to compute the symmetric product of two given operators $L_1,L_2$. In this paper we consider the corresponding division problem:
Lixin Du, Manuel Kauers
openaire   +2 more sources