Results 111 to 120 of about 328,940 (311)
Dissipative Boundary Conditions for Ordinary Differential Operators
In this paper two theorems which describe dissipative boundary conditions for ordinary differential operators on a closed interval are proved. We also show that all these boundary conditions are Birkhoff regular in even case. In odd case this is not true and we bring an example which demonstrates it.
openaire +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Analytical method for solving linear abstract differential equations of order n
In this paper, the concept of point-wise independent set of closed operators is introduced. The new concept together with the use of Hahn–Banach Theorem enable us to reduce an inhomogeneous linear abstract differential equation of order n namely, Anu(n ...
Waseem Ghazi Alshanti +3 more
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Andrzej Lasota's selected results [PDF]
In this article we recall Andrzej Lasota's selected results which either indicated new directions of research, or layed the foundations for new approaches, or solved interesting problems. The area of mathematical interests of Professor Andrzej Lasota was
Józef Myjak
doaj
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Operational Solution of Non-Integer Ordinary and Evolution-Type Partial Differential Equations
A method for the solution of linear differential equations (DE) of non-integer order and of partial differential equations (PDE) by means of inverse differential operators is proposed.
Konstantin V. Zhukovsky +1 more
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
This paper examines fractional multi-time scale stochastic functional differential equations that, in addition, are driven by fractional noises. Based on a specially crafted fixed-point principle for the so-called “local operators”, we prove a Peano-type
Arcady Ponosov, Lev Idels
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Spectrality of ordinary differential operators
AmsLaTeX, 26 pages, added section on dissipative operators and ...
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RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source

