LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang +12 more
wiley +1 more source
Features of formation and neutralization of environmentally hazardous CrO₃ in chromium pyrometallurgy. [PDF]
Akberdin A +3 more
europepmc +1 more source
Oil- and Fuel-Resistant Rubber for Pressure Hoses Containing Carbon-Based Technological Waste as a Filler. [PDF]
Nakyp A +6 more
europepmc +1 more source
Abstract Background The optimal design for care delivery in Parkinson's disease (PD) that addresses changing needs of the lived experience is unclear. There is a critical need for care models to be implemented and transferable across diverse healthcare systems with agility.
Deepa Dash +34 more
wiley +1 more source
Comparative Analysis of Industrial Fused Magnesia from Natural and Flotation-Processed Magnesite: Associations Among CaO/SiO<sub>2</sub> Ratio, Silicate Phase Formation, and Microcracking. [PDF]
Wang C +5 more
europepmc +1 more source
It Is Personal: What People with Parkinson's Disease Say Matters Most for Quality of Life
Abstract Background Little is known about what matters most for quality of life in people with Parkinson's disease and how much it varies between individuals. Objective The goal was to define the relative impact of quality of life determinants in people with Parkinson's disease, including variation across individuals and by disease severity, gender ...
Samantha Dorrance +13 more
wiley +1 more source
Bridging the Gap in Carbon Free Iron Making: How Hydrogen Affects the Reduction of Iron Ore between 900 and 1590 °C. [PDF]
Mohanta RK +6 more
europepmc +1 more source
Abstract Background The first International Parkinson and Movement Disorder Society Evidence‐Based Medicine (MDS‐EBM) review for essential tremor (ET) was published in 2019; since then, the modified Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology was adopted by MDS, and new evidence exists.
Deepa Dash +12 more
wiley +1 more source
Real time 3D monitoring of sintering ore temperature enabled by temporal fusion transformers. [PDF]
Jiang Y +10 more
europepmc +1 more source
Monoaminergic Networks of Cognitive and Behavioral Symptoms in Early Parkinson's Disease
Abstract Background Parkinson's disease (PD) is associated with several behavioral and cognitive symptoms, the neurobiological background of which is not yet fully understood. Objectives The aim was to investigate the association between monoamine function and four specific nonmotor symptoms in early PD using the Parkinson's Progression Markers ...
Kalle J. Niemi +3 more
wiley +1 more source

