Genome sequence of canine herpesvirus [PDF]
Canine herpesvirus is a widespread alphaherpesvirus that causes a fatal haemorrhagic disease of neonatal puppies. We have used high-throughput methods to determine the genome sequences of three viral strains (0194, V777 and V1154) isolated in the United ...
Davison, Andrew +5 more
core +20 more sources
Bacterial riboproteogenomics : the era of N-terminal proteoform existence revealed [PDF]
With the rapid increase in the number of sequenced prokaryotic genomes, relying on automated gene annotation became a necessity. Multiple lines of evidence, however, suggest that current bacterial genome annotations may contain inconsistencies and are ...
Fijalkowska, Daria +3 more
core +2 more sources
Additional ORFs in Plant LTR-Retrotransposons
LTR-retrotransposons share a common genomic organization in which the 5′ long terminal repeat (LTR) is followed by the gag and pol genes and terminates with the 3′ LTR.
Carlos M. Vicient, Josep M. Casacuberta
doaj +1 more source
Developmental regulation of canonical and small ORF translation from mRNAs
Background Ribosomal profiling has revealed the translation of thousands of sequences outside annotated protein-coding genes, including small open reading frames of less than 100 codons, and the translational regulation of many genes.
Pedro Patraquim +4 more
doaj +1 more source
REPARATION : ribosome profiling assisted (re-)annotation of bacterial genomes [PDF]
Prokaryotic genome annotation is highly dependent on automated methods, as manual curation cannot keep up with the exponential growth of sequenced genomes.
Giess, Adam +5 more
core +1 more source
The effect of small inter-pulsar distance variations in stochastic gravitational wave background searches with Pulsar Timing Arrays [PDF]
One of the primary objectives for Pulsar Timing Arrays (PTAs) is to detect a stochastic background generated by the incoherent superposition of gravitational waves (GWs), in particular from the cosmic population of supermassive black hole binaries ...
Mingarelli, Chiara M. F., Sidery, Trevor
core +3 more sources
Diel transcriptional response of a California Current plankton microbiome to light, low iron, and enduring viral infection. [PDF]
Phytoplankton and associated microbial communities provide organic carbon to oceanic food webs and drive ecosystem dynamics. However, capturing those dynamics is challenging. Here, an in situ, semi-Lagrangian, robotic sampler profiled pelagic microbes at
Allen, AE +12 more
core +2 more sources
Using purine skews to predict genes in AT-rich poxviruses
Background Clusters or runs of purines on the mRNA synonymous strand have been found in many different organisms including orthopoxviruses. The purine bias that is exhibited by these clusters can be observed using a purine skew and in the case of ...
Upton Chris, Da Silva Melissa
doaj +1 more source
The Hidden Enemy Within: Non-canonical Peptides in Virus-Induced Autoimmunity
Viruses play a key role in explaining the pathogenesis of various autoimmune disorders, whose underlying principle is defined by the activation of autoreactive T-cells.
Manivel Lodha +3 more
doaj +1 more source
Translation and natural selection of micropeptides from long non-canonical RNAs
Translation of 100 to 300 micropeptides from small ORFs within lncRNA was detected by Ribosomal Profiling in Drosophila embryos. These translated small ORFs showed natural selection conserving micropeptide sequence and function.
Pedro Patraquim +4 more
doaj +1 more source

