Results 231 to 240 of about 150,284 (337)

An evaluation of the ecological niche of Orf virus (Poxviridae): Challenges of distinguishing broad niches from no niches

Rahul Raveendran Nair, Yoshinori Nakazawa, A. Townsend Peterson   +2 more
openalex   +2 more sources

A11 Peptide Enhances Radiosensitivity by Degrading EphA2 in Nasopharyngeal Carcinoma

Cancer Science, EarlyView.
In EphA2‐high‐expressing nasopharyngeal carcinoma cells, radiation triggers RSK‐dependent phosphorylation of EphA2 at Ser897, which in turn activates AKT and promote radioresistance. The A11 peptide breaks this signaling cascade by degrading EphA2 and blocking its S897 phosphorylation, thereby markedly enhancing radiosensitivity.
Ming Zhang, Zhi‐Qiang Xiao, Wei Huang, Shan‐Shan Lu, Hong Yi, Juan Feng   +5 more
wiley   +1 more source

De Novo Genes: Current Status and Future Goals. [PDF]

Genome Biol Evol
Casola C, Luria V, Vakirlis N, Zhao L.
europepmc   +1 more source

LncRNA H19‐Encoded Micropeptide altH19 Promotes DNA Replication and Mitosis in Myeloma Cells by Enhancing the Phosphorylation of CDK2 at Threonine 160

Cell Proliferation, EarlyView.
The micropeptide altH19 interacts with phosphorylated CDK2 (p‐CDK2), subsequently activating CDK2 phosphorylation. This enhances the downstream E2F1 target gene RB activity, which accelerates DNA replication, ultimately leading to rapid myeloma cell mitosis and proliferation.
Yaxin Zhang, Wenjing Li, Xu Cao, Jiwei Mao, Xiaodan Zhou, Linlin Liu, Ruosi Yao   +6 more
wiley   +1 more source

Development of new <i>Thermus thermophilus-Escherichia coli</i> shuttle vectors. [PDF]

Appl Environ Microbiol
Murayama S, Omichi H, Doi T, Miyazaki K, Tomita H, Honda K.   +5 more
europepmc   +1 more source

Climate shocks, democratization and (a culture of) cooperation

Economica, EarlyView.
Abstract While the direct economic effects of adverse climate shocks are well known, their indirect institutional impact is still poorly understood. To clarify this, we test the idea that adverse climate shocks push time‐inconsistent elites to enact inclusive political institutions, and non‐elites to embrace strong norms of cooperation.
Giacomo Benati, Carmine Guerriero
wiley   +1 more source

Translational regulation plasticity shapes wheat grain adaptation to heat stress. [PDF]

Genome Biol
Chen Y, Guo Y, Ma M, Wang Y, Guo W, Hu Z, Xin M, Yao Y, Ni Z, Sun Q, Peng H.   +10 more
europepmc   +1 more source

A novel kirkovirus may be associated with equine gastrointestinal disease

Equine Veterinary Journal, EarlyView.
Abstract Background Many cases of equine enterocolitis are suspected to be infectious in nature, but no pathogen is identified in many cases. Objectives Perform next‐generation sequencing on faeces collected from cases of equine enterocolitis for the presence of novel viruses and determine if an identified novel virus is associated with cases of equine
Lillian M. B. Haywood, Ava Clark, Ben Hause, Breanna Sheahan   +3 more
wiley   +1 more source

Augmenting microbial phylogenomic signal with tailored marker gene sets. [PDF]

Nat Commun
Secaira-Morocho H, Jiang X, Zhu Q.
europepmc   +1 more source

Human FASTK preferentially binds single‐stranded and G‐rich RNA

The FEBS Journal, EarlyView.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak, Dawid A. Dzadz, Mikołaj I. Kuska, Madhuri Kanavalli, Maria M. Klimecka, Matthew Merski, Katarzyna J. Bandyra, Maria W. Górna   +7 more
wiley   +1 more source