Results 21 to 30 of about 681,124 (262)

Intra-abdominal hypertension and abdominal compartment syndrome in pancreatitis, paediatrics, and trauma [PDF]

, 2015
Intra-abdominal hypertension (IAH) is an important contributor to early organ dysfunction in trauma and sepsis. However, relatively little is known about the impact of intra-abdominal pressure (IAP) in general internal medicine, pregnant patients, and ...
De Keulenaer, Bart L, De laet, Inneke, De Waele, Jan, Ejike, Janeth C, Ivatury, Rao, Kimball, Edward, Kirkpatrick, Andrew W, Leppäniemi, Ari, Malbrain, Manu LNG, Roberts, Derek J   +9 more
core   +1 more source

Association between intraoperative end-tidal carbon dioxide and postoperative organ dysfunction in major abdominal surgery: A cohort study.

PLoS ONE, 2023
BackgroundData on the effects of intraoperative end-tidal carbon dioxide (EtCO2) levels on postoperative organ dysfunction are limited. Thus, this study was designed to investigate the relationship between the intraoperative EtCO2 level and postoperative
Li Dong, Chikashi Takeda, Tsukasa Kamitani, Miho Hamada, Akiko Hirotsu, Yosuke Yamamoto, Toshiyuki Mizota   +6 more
doaj   +1 more source

Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications [PDF]

, 2016
This article reports the conclusions of the second part of a consensus expert conference on the nomenclature of renal replacement therapy (RRT) techniques currently utilized to manage acute kidney injury and other organ dysfunction syndromes in ...
Bagshaw, S. M., Balducci, A., Baldwin, I., Barbarigo, F., Bellomo, R., Bellomo, Rinaldo, Braganã³, P., Braunsky, J., Calletti, F., Cerda, J., Cerda, Jorge, Chawla, L., De Gaudio, A. Raffaele, De Rosa, S., De Rosa, Silvia, Di Somma, S., Doi, K., Dosil Rosende, P., Emmett, M., Fecondini, L., Galavotti, D., Garzotto, F., Garzotto, Francesco, Gibney, N., Goldstein, S. L., Guadagni, G., Honore, Patrick M., Honorã, P., Hoste, E., Inadome, S., Kashani, K., Katz, N., Kellum, J., Kenley, R., Kobayashi, Y., Lannoy, J., Lewington, A., Lorenzin, Anna, Mariano, F., Mccullough, P. A., Mehta, R. L., Menneguerre, J., Mettifogo, M., Neri, M., Neri, Mauro, Ostermann, M., Pani, A., Payen, Didier, Pirazzoli, P., Pohlmeier, R., Pouchoulin, D., Ricci, Z., Ricci, Zaccaria, Ronco, C., Ronco, Claudio, Rosner, M., Samoni, Sara, Seamann, M., Shaw, A., Tolwani, A., Villa, G., Villa, Gianluca, Vincent, J. L., Vincent, Jean-Louis, Wendon, J., Wendon, Julia, Zaccaria, Marta   +66 more
core   +4 more sources

Natural compounds targeting mitochondrial dysfunction: emerging therapeutics for target organ damage in hypertension

Frontiers in Pharmacology, 2023
Hypertension generally causes target organ damage (TOD) in the heart, brain, kidney, and blood vessels. This can result in atherosclerosis, plaque formation, cardiovascular and cerebrovascular events, and renal failure. Recent studies have indicated that
Xiaolin Liao, Yuanshan Han, Ying He, Jianjun Liu, Yuhong Wang   +4 more
doaj   +1 more source

Lipid Profile as a Predictive Marker for Organ Dysfunction after Thoracoabdominal Surgery: A Cross-sectional Study [PDF]

Iranian Journal of Medical Sciences, 2023
Background: Plasma total cholesterol is considered a negative acute phase reactant. In various pathological conditions, such as trauma, sepsis, burns, and liver dysfunction, as well as post-surgery, serum cholesterol level decreases.
Sarvin Sanaie, Sanam Dolati, Majid Montazer, Sarina Ranjbari, Arezoo Fathalizadeh, Kamran Shadvar, Elnaz Faramarzi, Ata Mahmoodpoor   +7 more
doaj   +1 more source

Levosimendan for the prevention of acute organ dysfunction in sepsis [PDF]

, 2016
BACKGROUND Levosimendan is a calcium-sensitizing drug with inotropic and other properties that may improve outcomes in patients with sepsis. METHODS We conducted a double-blind, randomized clinical trial to investigate whether levosimendan reduces the ...
Al-Beidh, F, Ashby, D, Best-Lane, J, Brealey, D, Breen, A, Cross, M, Gordon, AC, Liu, KD, Mason, AJ, McAuley, DF, McNamee, JJ, Nutt, CL, Orme, RML, Perkins, GD, Reschreiter, H, Santhakumaran, S, Singer, M   +16 more
core   +2 more sources

Upregulating Nonneuronal Cholinergic Activity Decreases TNF Release from Lipopolysaccharide-Stimulated RAW264.7 Cells

Mediators of Inflammation, 2014
Nonneuronal cholinergic system plays a primary role in maintaining homeostasis. It has been proved that endogenous neuronal acetylcholine (ACh) could play an anti-inflammatory role, and exogenous cholinergic agonists could weaken macrophages inflammatory
Yi Lv, Sen Hu, Jiangyang Lu, Ning Dong, Qian Liu, Minghua Du, Huiping Zhang   +6 more
doaj   +1 more source

Role of the microbiome, probiotics, and 'dysbiosis therapy' in critical illness. [PDF]

, 2016
Purpose of reviewLoss of 'health-promoting' microbes and overgrowth of pathogenic bacteria (dysbiosis) in ICU is believed to contribute to nosocomial infections, sepsis, and organ failure (multiple organ dysfunction syndrome).
Knight, Rob, McDonald, Daniel, Wischmeyer, Paul E   +2 more
core   +2 more sources

Machine learning in critical care: state-of-the-art and a sepsis case study

BioMedical Engineering OnLine, 2018
Background Like other scientific fields, such as cosmology, high-energy physics, or even the life sciences, medicine and healthcare face the challenge of an extremely quick transformation into data-driven sciences.
Alfredo Vellido, Vicent Ribas, Carles Morales, Adolfo Ruiz Sanmartín, Juan Carlos Ruiz Rodríguez   +4 more
doaj   +1 more source

Identifying patients at risk for augmented renal clearance in the ICU : limitations and challenges [PDF]

, 2013
Augmented renal clearance (ARC) is an important determinant of antibiotic exposure in critically ill patients, and identifying patients at risk is therefore an important goal.
Carlier, Mieke, De Waele, Jan
core   +2 more sources