Results 61 to 70 of about 681,124 (262)
Energetic dysfunction in sepsis: a narrative review
Annals of Intensive Care, 2021 Background Growing evidence associates organ dysfunction(s) with impaired metabolism in sepsis. Recent research has increased our understanding of the role of substrate utilization and mitochondrial dysfunction in the pathophysiology of sepsis-related ...
Sebastien Preau +14 more
doaj +1 more source
Practical approach on frail older patients attended for acute heart failure [PDF]
, 2016 Acute heart failure (AHF) is a multi-organ dysfunction syndrome. In addition to known cardiac dysfunction, non-cardiac comorbidity, frailty and disability are independent risk factors of mortality, morbidity, cognitive and functional decline, and risk of
Bueno, H +15 more
core +4 more sources
Advanced ScienceTrained immunity induced by β‐glucan insult drives the functional reprogramming of macrophages to the hyperinflammatory status, contributing to developing or maintaining inflammatory diseases.
Haibo Su +12 more
doaj +1 more source
Multiple Organ Dysfunction After Cardiosurgical Interventions
Общая реаниматология, 2010 Objective: to study the clinical efficiency of introducing an algorithm for organ-protective intensive care. Materials and methods. 3278 case histories of patients admitted to the clinic in 2000—2009 for surgical treatment (under extracorporeal ...
L. S. Barbarash +7 more
doaj +1 more source
Genetic, Physiological, and Pharmacological Amelioration of Ischemic Injury [PDF]
, 2010 Organ transplantation is the treatment of choice for end stage organ failure, and in recent decades one year results have greatly improved. Two major problems facing the transplant community remain; long-term survival of organ grafts has still not ...
Susa, D. (Denis)
core +1 more source
Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock. [PDF]
, 2009 The 5-lipoxygenase (5-LO) pathway is responsible for the production of leukotrienes (LTs), inflammatory lipid mediators which play a role in innate immunity. More recently, a pivotal role of LTs in ischemia-reperfusion and shock injury has been suggested.
CUZZOCREA S +2 more
core +1 more source
What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension [PDF]
, 2015 The effects of increased intra-abdominal pressure (IAP) on cardiovascular function are well recognized and include a combined negative effect on preload, afterload and contractility.
De Keulenaer, Bart L +2 more
core +1 more source
PROTECTIVE MECHANICAL VENTILATION IN PATIENTS WITHOUT OR WITH LUNG INJURY [PDF]
Sanamed, 2014 The mortality of Acute Respiratory Distress Syndrome (ARDS) is still high from 27 to 45% according to Berlin definition. Even in surgical patients without lung injury, the postoperative pulmonary complications (PPCs) are frequent.
Sutherasan Yuda +3 more
doaj
Annals of Intensive Care, 2019 Background The mechanisms of organ failure during sepsis are not fully understood. The hypothesis of circulating factors has been suggested to explain septic myocardial dysfunction.
Keyvan Razazi +9 more
doaj +1 more source
Levels of protein C and soluble thrombomodulin in critically ill patients with acute kidney injury: a multicenter prospective observational study. [PDF]
, 2015 Endothelial dysfunction contributes to the development of acute kidney injury (AKI) in animal models of ischemia reperfusion injury and sepsis. There are limited data on markers of endothelial dysfunction in human AKI. We hypothesized that Protein C (PC)
Berg, David T +10 more
core +3 more sources