Results 121 to 130 of about 1,992,155 (390)

Cryopreservation of a whole liver [PDF]

, 2007
Preservation of vascularized organs such as the liver is limited to 24hrs. before destructive processes disqualify it for transplantation. This narrow time window prevents surgeons from performing optimal pathogen screening and matching tests which often
Amir Arav, Menahem Ben-Haim, Zohar Gavish   +2 more
core   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Machine Perfusion for Abdominal Organ Preservation: A Systematic Review of Kidney and Liver Human Grafts

Journal of Clinical Medicine, 2019
Introduction: To match the current organ demand with organ availability from the donor pool, there has been a shift towards acceptance of extended criteria donors (ECD), often associated with longer ischemic times.
M. Bellini, Mikhail Nozdrin, J. Yiu, V. Papalois   +3 more
semanticscholar   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy

Journal of Clinical Oncology, 2022
J. García-Aguilar, S. Patil, M. Gollub, Jin K. Kim, J. Yuval, Hannah M Thompson, F. Verheij, D. Omer, Meghan E. Lee, R. Dunne, J. Marcet, P. Cataldo, B. Polite, Daniel O. Herzig, D. Líška, S. Oommen, C. Friel, C. Ternent, A. Coveler, S. Hunt, A. Gregory, M. Varma, B. Bello, J. Carmichael, J. Krauss, A. Gleisner, P. Paty, M. Weiser, G. Nash, E. Pappou, José G. Guillem, L. Temple, I. Wei, M. Widmar, Sabrina T. Lin, N. Segal, A. Cercek, R. Yaeger, J. Smith, K. Goodman, A. Wu, L. Saltz   +41 more
semanticscholar   +1 more source

Partial and full arc with DynamicARC technique in pencil beam scanning proton therapy for bilateral head and neck cancer: A feasibility and dosimetric study

Journal of Applied Clinical Medical Physics, Volume 26, Issue 4, April 2025.
Abstract Purpose A novel proton beam delivery method known as DynamicARC spot scanning has been introduced. The current study aims to determine whether the partial proton arc technique, in conjunction with DynamicARC pencil beam scanning (PBS), can meet clinical acceptance criteria for bilateral head and neck cancer (HNC) and provide an alternative to ...
Suresh Rana, Noufal Manthala Padannayil, Shyam Pokharel, Hina Saeed, Michael Kasper   +4 more
wiley   +1 more source

Bioengineering approaches to organ preservation ex vivo

Experimental biology and medicine, 2019
The advent of successful solid organ transplantation is undoubtedly among the most significant medical achievements of the 20th century. Despite advances in the field of transplantation since its inception over 50 years ago, our approach to donor organ ...
M. Pinezich, G. Vunjak‐Novakovic
semanticscholar   +1 more source

Development of an automated CBCT‐based simulation‐free platform for expedited palliative radiotherapy on a conventional linear accelerator

Journal of Applied Clinical Medical Physics, Volume 26, Issue 4, April 2025.
Abstract Background Conventional approaches for emergent or expedited palliative radiotherapy (RT) involve the application of cumbersome vendor‐provided solutions and/or multiple patient appointments to complete the RT workflow within a compressed timeframe.
Riley C. Tegtmeier, Edward L. Clouser Jr., Quan Chen, Courtney R. Buckey, Suzanne J. Chungbin, Christopher J. Kutyreff, Jose S. Aguilar, Amber L. Labbe, Brooke L. Horning, William G. Rule, Sujay A. Vora, Yi Rong   +11 more
wiley   +1 more source

Prolonging Preservation or Assessment of Organ Quality—What is Key?

Transplant International, 2023
J. Eden, P. Dutkowski
doaj   +1 more source

Long-term Outcome of an Organ Preservation Program After Neoadjuvant Treatment for Rectal Cancer.

Journal of the National Cancer Institute, 2016
BACKGROUND The aim of this study was to establish the oncological and functional results of organ preservation with a watch-and-wait approach (W&W) and selective transanal endoscopic microsurgery (TEM) in patients with a clinical complete or near ...
M. Martens, M. Maas, L. Heijnen, D. Lambregts, J. Leijtens, L. Stassen, S. Breukink, C. Hoff, E. Belgers, J. Melenhorst, R. Jansen, J. Buijsen, T. Hoofwijk, R. Beets-Tan, G. Beets   +14 more
semanticscholar   +1 more source