This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao+16 more
wiley +1 more source
Deceased Organ Donor Management and Organ Distribution From Organ Procurement Organization-Based Recovery Facilities Versus Acute-Care Hospitals. [PDF]
Vail EA+6 more
europepmc +1 more source
Optimal production of transplant care services. [PDF]
Most organ transplants are from dead donors. National transplant organizations exhibit considerable differences in terms of their donor population rates. Spain’s organization is by far the most efficient in this respect.
Bruno Deffains, Jean Mercier Ythier
core
DISTANT PROCUREMENT OF ORGANS FOR CLINICAL HEART-LUNG TRANSPLANTATION USING A SINGLE-FLUSH TECHNIQUE
J. Wallwork+4 more
openalex +1 more source
Experience with an organ procurement organization‐based non‐directed living kidney donation programme [PDF]
Paula J. Mark+3 more
openalex +1 more source
Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng+10 more
wiley +1 more source
Organ donation in Malta : what’s new? [PDF]
Malta transposed Directive 2010/45/EU of the European Parliament and of the Council of 7 July 2010 on standards of quality and safety of human organs intended for transplantation (European Parliament and Council, 2010) on 12th October 2012 through ...
Ellul, Bridget
core
Cadaver Donor Renal Transplantation by Centers of the Southeastern Organ Procurement Foundation
John C. McDonald+6 more
openalex +2 more sources
Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li+6 more
wiley +1 more source
Smart match: revolutionizing organ allocation through artificial intelligence
In this transformative era of organ transplantation, integrating Smart Match and artificial intelligence (AI) emerges as a pivotal advancement, revolutionizing organ allocation processes.
Rajkiran Deshpande
doaj +1 more source