Results 331 to 340 of about 1,436,477 (401)

Sustainable One‐Pot Electrochemical Approach for Entrapment of Multi‐Enzymes and Biocompatible Redox Mediator

open access: yesChemPlusChem, EarlyView.
Novel enzyme‐modified carbon felt electrodes are constructed for efficient bio‐electrocatalysis. Simultaneous electrodeposition of pyrrole and neutral red provides a facile one‐step approach for enzyme immobilization. The biocompatible conductive polymer matrix performs for the entrapment of dehydrogenase enzymes on the electrode and ensures sufficient
Hathaichanok Seelajaroen   +6 more
wiley   +1 more source

Solvent Effect on Antimicrobial Hydrophilic Xerogel Coating of Medicinal Leathers in Simulated Industrial Finishing Process

open access: yesChemPlusChem, EarlyView.
Silica‐hyperbranched poly(ethylene imine) (PEI) xerogels incorporating silver nanoparticles coated titanium dioxide particles. Dual solvent dispersions of these composites enhance medical leathers′ hydrophilicity and antimicrobial properties. The nucleation of the metal ions into the dendritic polymer‘s cavities and the gel formation were inspired by ...
Theofanis Bompotis   +12 more
wiley   +1 more source

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

open access: yesDrug Testing and Analysis, EarlyView.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman   +9 more
wiley   +1 more source

Pancreas procurement from multiorgan donors for islet transplantation [PDF]

open access: yes, 1992
Casavilla, A   +6 more
core  

Identification and Investigation of the Intrinsic Receptor Activation Potential and Metabolization of the New Oxo‐Pyridyl Synthetic Cannabinoid Receptor Agonist CH‐FUBBMPDORA

open access: yesDrug Testing and Analysis, EarlyView.
Another Chinese generic ban‐evading SCRA, CH‐FUBBMPDORA, has emerged. This study reports its first identification in Europe, its analytical characterization (NMR, Raman, FTIR, GC–MS, and HRMS), its cannabinoid activation potential in a βarr2 recruitment assay, and its metabolization profile.
Marie H. Deventer   +13 more
wiley   +1 more source

Identification of Three Novel Tetrahydrocannabinol Analogs in the European Market

open access: yesDrug Testing and Analysis, EarlyView.
The major isolated ingredient of “CB9” was identified as [2‐(E)‐propen‐1‐yl]‐Δ8‐tetrahydrocannabinol‐acetate of “tresconol” as [2‐propen‐2‐yl]‐Δ9‐tetrahydrocannabinol and of “CBx” as [2‐propen‐2‐yl]‐Δ8‐tetrahydrocannabinol. These compounds have no available spectroscopic or chromatographic data and have never been identified in Cannabis plants, and ...
Evangelos Dadiotis   +4 more
wiley   +1 more source

Quantitative Investigation of Nitrosamine Drug Substance‐Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography–Tandem Mass Spectrometry and Structure–Activity Relationship Analysis

open access: yesDrug Testing and Analysis, EarlyView.
The study provides information about the impact of physiological gastric conditions on the unbeneficial occurrence of nitrosamine drug substance–related impurities (NDSRIs). Both main factors for nitrosation in the form of acidic conditions and the presence of nitrite were adequately chosen for triggering the conversion of drug compounds into NDSRIs ...
Matthias Vogel   +5 more
wiley   +1 more source

Achieving Sustainable Development Goals Through the Governance of Local Food Systems in Western Countries: A Realist Synthesis

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT Over the last decade, various studies have focused on the functioning of local food policy councils and their key role in institutionalizing participatory governance mechanisms involving stakeholders concerned with the promotion of sustainable food systems.
Laurence Guillaumie   +3 more
wiley   +1 more source

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